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艾滋病相关恶性肿瘤的趋势与生存率

Trends and survival in AIDS-associated malignancies.

作者信息

Casabona J, Salas T, Salinas R

机构信息

AIDS Program, Health Department, Generalitat de Catalunya, Barcelona, Spain.

出版信息

Eur J Cancer. 1993;29A(6):877-81. doi: 10.1016/s0959-8049(05)80430-7.

DOI:10.1016/s0959-8049(05)80430-7
PMID:8484982
Abstract

Data from 1569 AIDS cases reported to the population-based AIDS Registry of Catalonia have been analysed to describe the epidemiology and temporal evolution of both Kaposi's sarcoma (KS) and non-Hodgkin lymphoma (NHL). Of the 1569 cases reported, 53 (3.4%) presented with NHL and 135 (8.6%) with KS. KS cases were more frequent among homosexual/bisexual men and the age of KS cases was significantly higher than all others presenting diseases (38.22 years). NHL cases were more frequently among men but no significant age difference was found. The percentage of KS over time decreased significantly only among intravenous drug users. Cases presenting with a NHL had by far the worst prognosis (median survival time = 169 days). Biases affecting the measurement of AIDS associated malignancies (AAM) using surveillance data are analysed. The prevalence of AAM will increase during the next few years, and NHL may be one of the leading causes of death among AIDS patients in the near future.

摘要

对向加泰罗尼亚地区人群艾滋病登记处报告的1569例艾滋病病例的数据进行了分析,以描述卡波西肉瘤(KS)和非霍奇金淋巴瘤(NHL)的流行病学及时间演变情况。在报告的1569例病例中,53例(3.4%)患有NHL,135例(8.6%)患有KS。KS病例在同性恋/双性恋男性中更为常见,且KS病例的年龄显著高于所有其他所患疾病的病例(38.22岁)。NHL病例在男性中更为常见,但未发现显著的年龄差异。仅在静脉吸毒者中,KS的比例随时间显著下降。患有NHL的病例预后最差(中位生存时间 = 169天)。分析了使用监测数据影响艾滋病相关恶性肿瘤(AAM)测量的偏差。未来几年AAM的患病率将会增加,NHL可能在不久的将来成为艾滋病患者的主要死亡原因之一。

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