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一种可培养的抗酸菌与麻风分枝杆菌的抗原相似性。

Antigenic similarity of a cultivable acid fast bacterium to Mycobacterium leprae.

作者信息

Joshi S, Nair S C, Mahadevan P R

机构信息

Foundation for Medical Research, Bombay.

出版信息

Indian J Med Res. 1993 Jan;97:18-24.

PMID:8486404
Abstract

A cultivable acid fast stainable bacterium obtained from leprosy nodule showed similarity to M. leprae in antigenicity to serum antibodies of lepromatous leprosy patients. The antigenic similarity has been seen more clearly in the delipidified cell components of both these bacteria. An antigen of 35-38 kDa has been seen as a common antigen between M. leprae and the cultivable bacilli with binding ability to sera from leprosy patients. This cultivable bacterial component could be used for serodiagnosis of lepromatous leprosy.

摘要

从麻风结节中分离出的一种可培养的抗酸染色细菌,在抗原性上与麻风分枝杆菌相似,与瘤型麻风患者的血清抗体反应。这种抗原相似性在这两种细菌的脱脂细胞成分中表现得更为明显。35-38 kDa的抗原被视为麻风分枝杆菌和可培养杆菌之间的共同抗原,它能与麻风患者的血清结合。这种可培养细菌成分可用于瘤型麻风的血清学诊断。

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