Amon M, Menapace R
1. Universität Augenklinik Wien, Vienna, Austria.
J Cataract Refract Surg. 1993 Mar;19(2):258-62. doi: 10.1016/s0886-3350(13)80953-4.
A prospective in vivo study of 50 intraocular lenses was done to document the long-term results and biocompatibility of heparin-surface-modified poly(methyl methacrylate) posterior chamber lenses. Continuous curvilinear capsulorhexis and phacoemulsification were performed throughout and examinations were by slit-lamp and specular microscopy. Decentrations of more than 1 mm were seen in 4% of eyes. Stress folds from the haptic traction forces were detected in 16%. A posterior capsulotomy was performed in 10% because of fibrosis or Elschnig pearl formation. Fine fibers were found on the lens surface in 76%. During the first postoperative days only a moderate number of fibroblast-like cells was observed. Foreign-body giant cells were seen in 8%. All cases with foreign-body giant cells had posterior synechias. Visual performance and clinical results were comparable to those of other well-approved intraocular lenses. The low percentage of cellular reaction on the lens surface suggests good biocompatibility.
对50个人工晶状体进行了一项前瞻性体内研究，以记录肝素表面修饰的聚甲基丙烯酸甲酯后房型人工晶状体的长期效果和生物相容性。全程采用连续环形撕囊和超声乳化术，并通过裂隙灯和镜面显微镜进行检查。4%的眼睛出现了超过1毫米的偏心。16%的眼睛检测到因襻牵引力量导致的应力褶皱。10%的眼睛因纤维化或Elschnig珠形成而进行了后囊切开术。76%的人工晶状体表面发现了细纤维。术后最初几天仅观察到数量适中的成纤维细胞样细胞。8%的眼睛出现了异物巨细胞。所有出现异物巨细胞的病例均有后粘连。视觉性能和临床结果与其他已获充分认可的人工晶状体相当。人工晶状体表面细胞反应的低发生率表明其具有良好的生物相容性。
