Cohen R B, Wilcox C W
Keesler Medical Center, Miss.
Oral Surg Oral Med Oral Pathol. 1993 May;75(5):583-6. doi: 10.1016/0030-4220(93)90229-w.
Acromegaly results from the over production of growth hormone after the age at which the epiphyses of the bones have fused. The most common cause is an adenoma of the anterior pituitary gland. Early signs and symptoms are subtle and delayed diagnosis is common. The health consequences of untreated acromegaly are considerable. A brief description of the condition is given and a case report is included. The condition of the patient was first diagnosed after a dental examination at which he voiced a complaint of the inability to incise and a progressive open bite that he attributed to prosthetic treatment. On the basis of his intraoral radiograph history, it is probable that he developed the disease more than 5 years before its diagnosis.
肢端肥大症是由于骨骼骨骺融合后生长激素分泌过多所致。最常见的病因是垂体前叶腺瘤。早期症状不明显，诊断往往延迟。未经治疗的肢端肥大症对健康的影响相当大。本文对该病症进行了简要描述，并包含一个病例报告。该患者的病情最初是在一次牙科检查后被诊断出来的，当时他主诉无法切割食物，且有逐渐加重的开颌畸形，他认为这是假牙治疗导致的。根据他的口腔X光片病史，很可能在确诊该病5年多以前他就已患病。
