Borak J, Cieślicki J, Szelenberger W, Wilczak-Szadkowska H, Koziej M, Zieliński J
Kliniki Chorób Płuc Instytutu Gruźlicy i Chorób Płuc, Warszawie.
Psychiatr Pol. 1993 Jan-Feb;27(1):43-55.
The aim of the research was to discover the level of change observed in cognitive functions and personality variables in patients ill with obstructive sleep apnea prior to and after CPAP treatment. Data was collected from 20 male patients ill with a severe form of obstructive sleep apnea whose physiological symptoms were correlated with the results of cognitive functions and personality variables. It was concluded that obstructive sleep apnea patients have lowered; attention, concentration, speed of learning verbal and visual stimuli and speed of learning visual-motor tasks. An increased level of depression was noted together with increased anxiety and psychological tension. In half of the group irregular EEG recordings and a pathological result on the Benton Test suggests organic damage to the CNS. These changes were negatively correlated with amounts of REM and 3 + 4 NREM sleep, but were positively correlated with the level of sleep hypoxemia. The results suggest that after 3 months of CPAP treatment affect improved significantly. The observed tendency for cognitive functions to improved was not statistically significant.
该研究的目的是发现阻塞性睡眠呼吸暂停患者在持续气道正压通气（CPAP）治疗前后认知功能和人格变量的变化程度。数据收集自20名患有严重阻塞性睡眠呼吸暂停的男性患者，其生理症状与认知功能和人格变量的结果相关。研究得出结论，阻塞性睡眠呼吸暂停患者的注意力、专注力、学习言语和视觉刺激的速度以及学习视觉运动任务的速度均有所降低。抑郁水平升高，同时焦虑和心理紧张加剧。该组中有一半人的脑电图记录不规则，并且在本顿测试中结果异常，提示中枢神经系统存在器质性损伤。这些变化与快速眼动（REM）睡眠和3+4期非快速眼动（NREM）睡眠量呈负相关，但与睡眠低氧血症水平呈正相关。结果表明，经过3个月的CPAP治疗后，情况有了显著改善。观察到的认知功能改善趋势在统计学上并不显著。
