Caminero A B, Pareja J A, Millán I, de Pablos M J
Unidad de Neurología, Hospital Nuestra Señora de Sonsoles, Avila.
Neurologia. 1997 Aug-Sep;12(7):281-6.
The conventional study of obstructive sleep apnea syndrome (OSAS) requires two polysomnographic recordings on two different nights, one for diagnosis and the other for determining an effective level of continuous positive airway pressure (CPAP). In this study we examined an alternative method requiring a single night of polysomnographic recording encompassing both diagnostic and treatment functions. In order to obtain recordings of all phases of sleep, as well as recordings taken in supine decubitus position, the duration of polysomnographic readings was individualized ("made to order" polysomnograms). A single-night session was sufficient for diagnosis and for adjusting treatment in most cases. In some cases the night was extended well into the morning hours in an effort to obtain all the necessary data. "Made-to-order" polysomnograms were compared to traditional ones by contrasting breathing parameters (the U of Mann Whitney) and sleep architecture findings for two groups of men diagnosed consecutively of OSAS. Thirty-four patients were studied over two nights (mean age: 50 years; BMI 37 Kg/m2). Forty-six patients (mean age: 49 years; BMI: 38 Kg/m2) were studied in single-night sessions. The differences between the two groups were not significant. For most patients studied in "made to order" sessions, all sleep stages were recorded and readings were taken in supine position. REM sleep was not recorded, however, for 26% of the patients in this group. No significant differences between the double- and single-session groups were found for apnea (51 versus 62), maximum oxygen desaturation (72% versus 75%) and effective CPAP level (9 versus 10 cm H2O). These data suggest that both study methods are equally useful for evaluating OSAS severity and for prescribing effective CPAP treatment. We discuss, however, the need to arrange for two-night studies in the minority of patients for whom no REM sleep recordings become available during a single session.
阻塞性睡眠呼吸暂停综合征(OSAS)的传统研究需要在两个不同的夜晚进行两次多导睡眠图记录,一次用于诊断,另一次用于确定持续气道正压通气(CPAP)的有效水平。在本研究中,我们研究了一种替代方法,该方法只需一个晚上的多导睡眠图记录,即可同时具备诊断和治疗功能。为了获得睡眠各阶段的记录以及仰卧位时的记录,多导睡眠图读数的时长是个性化的(“定制”多导睡眠图)。在大多数情况下,一个晚上的记录就足以进行诊断和调整治疗。在某些情况下,会将记录时间延长至凌晨,以获取所有必要数据。通过对比两组连续诊断为OSAS的男性的呼吸参数(曼-惠特尼U检验)和睡眠结构结果,将“定制”多导睡眠图与传统多导睡眠图进行了比较。对34名患者进行了两晚的研究(平均年龄:50岁;体重指数37 Kg/m2)。对46名患者(平均年龄:49岁;体重指数:38 Kg/m2)进行了一晚的记录。两组之间的差异不显著。在“定制”记录中研究的大多数患者,所有睡眠阶段均有记录,且在仰卧位进行了读数。然而,该组中有26%的患者未记录到快速眼动(REM)睡眠。在呼吸暂停(51次对62次)、最大氧饱和度下降(72%对75%)和有效CPAP水平(9 cmH2O对10 cmH2O)方面,双记录组和单记录组之间未发现显著差异。这些数据表明,两种研究方法在评估OSAS严重程度和开具有效的CPAP治疗处方方面同样有用。然而,我们讨论了对于少数在单次记录中未获得REM睡眠记录的患者,需要安排两晚研究的必要性。