Kotlarek-Haus S, Gabryś K, Kuliszkiewicz-Janus M, Potoczek S, Kiełbiński M
Katedry i Kliniki Hematologii Akademii Medycznej, Wrocławiu.
Acta Haematol Pol. 1993;24(1):35-42.
61 patients with Hodgkin's disease, i.e., 40.9% of all HD pts hospitalized in the years 1970-1981 are more than 10 years survivors: 46 are alive and 15 died of underlying disease or its complications. The most important prognostic factor at diagnosis was clinical advancement and the form A or B of HD. Age and sex also influenced survival but to a lesser degree. Patients living in CCR were more likely to have MC histology than those with relapsing disease, who more often showed LD and LP type. Among 5 persons with second neoplasms four disclosed NS type of HD. No statistical differences in clinical prognostic factors were encountered between further alive and those who died after more than 10-yrs. Almost all patients were able to normally continue their familial and professional lives.
61例霍奇金病患者，即1970 - 1981年间住院的所有霍奇金病患者中有40.9%存活超过10年：46例仍在世，15例死于基础疾病或其并发症。诊断时最重要的预后因素是临床分期以及霍奇金病的A或B型。年龄和性别也影响生存，但程度较小。与复发疾病患者相比，处于持续完全缓解（CCR）状态的患者更有可能具有混合细胞（MC）组织学类型，复发疾病患者更常表现为淋巴细胞消减（LD）和淋巴细胞为主（LP）型。在5例发生第二肿瘤的患者中，有4例表现为结节硬化（NS）型霍奇金病。存活超过10年的患者与死亡患者在临床预后因素方面未发现统计学差异。几乎所有患者都能够正常继续其家庭和职业生活。
