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[一名鳞状细胞肺癌患者在接受顺铂和依托泊苷联合化疗完全缓解后的无病生存期]

[Disease-free survival in a patient with squamous cell lung carcinoma following complete response with the combination chemotherapy of cisplatin and etoposide].

作者信息

Taniwaki M, Kakusui M, Imoto M, Takashima T, Misawa S, Kashima K

机构信息

Third Dept. of Internal Medicine, Kyoto Prefectural University of Medicine.

出版信息

Gan To Kagaku Ryoho. 1993 May;20(7):949-52.

PMID:8489301
Abstract

Disease-free survival is reported in a patient with non-small cell lung carcinoma successfully treated with the combination chemotherapy of cisplatin and etoposide (CDDP-ETOP). An 80-year-old woman was diagnosed as having squamous cell carcinoma of the lung with bone metastasis. Chest X-ray showed a tumor (64 x 68 mm in size) in the S1/4 segment of the right lobe, and CT scan revealed no apparent metastasis of hilar lymphnode. In March 1989, the patient achieved a complete response (CR) after two courses of CDDP-ETOP therapy, followed by ETOP(100mg) every two weeks and daily UFT (400 mg) for 10 months. Subsequently, a single course of CDDP-ETOP was administered as a consolidation therapy. The patient is alive with no evidence of recurrent disease for 3 years and half after achieving CR.

摘要

一名非小细胞肺癌患者经顺铂和依托泊苷联合化疗(CDDP - ETOP)成功治疗后实现无病生存。一名80岁女性被诊断为肺鳞状细胞癌伴骨转移。胸部X线显示右叶S1/4段有一肿瘤(大小为64×68mm),CT扫描未显示肺门淋巴结有明显转移。1989年3月,患者在接受两个疗程的CDDP - ETOP治疗后达到完全缓解(CR),随后每两周给予依托泊苷(100mg)并每日给予优福定(400mg),持续10个月。随后给予一个疗程的CDDP - ETOP作为巩固治疗。患者在达到CR后已存活3年半,无疾病复发迹象。

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