Taniwaki M, Kakusui M, Imoto M, Takashima T, Misawa S, Kashima K
Third Dept. of Internal Medicine, Kyoto Prefectural University of Medicine.
Gan To Kagaku Ryoho. 1993 May;20(7):949-52.
Disease-free survival is reported in a patient with non-small cell lung carcinoma successfully treated with the combination chemotherapy of cisplatin and etoposide (CDDP-ETOP). An 80-year-old woman was diagnosed as having squamous cell carcinoma of the lung with bone metastasis. Chest X-ray showed a tumor (64 x 68 mm in size) in the S1/4 segment of the right lobe, and CT scan revealed no apparent metastasis of hilar lymphnode. In March 1989, the patient achieved a complete response (CR) after two courses of CDDP-ETOP therapy, followed by ETOP(100mg) every two weeks and daily UFT (400 mg) for 10 months. Subsequently, a single course of CDDP-ETOP was administered as a consolidation therapy. The patient is alive with no evidence of recurrent disease for 3 years and half after achieving CR.
一名非小细胞肺癌患者经顺铂和依托泊苷联合化疗(CDDP - ETOP)成功治疗后实现无病生存。一名80岁女性被诊断为肺鳞状细胞癌伴骨转移。胸部X线显示右叶S1/4段有一肿瘤(大小为64×68mm),CT扫描未显示肺门淋巴结有明显转移。1989年3月,患者在接受两个疗程的CDDP - ETOP治疗后达到完全缓解(CR),随后每两周给予依托泊苷(100mg)并每日给予优福定(400mg),持续10个月。随后给予一个疗程的CDDP - ETOP作为巩固治疗。患者在达到CR后已存活3年半,无疾病复发迹象。