Stoler M H
Department of Anatomic Pathology, Cleveland Clinic Foundation, OH 44195.
Arch Pathol Lab Med. 1993 May;117(5):478-81.
In situ hybridization is the molecular method for localizing nucleic acid targets in the context of histomorphology. As such, it has tremendous potential application in research and diagnostic pathology. This essay attempts to briefly review the in situ method and to clarify its position as an emerging clinically useful technology.
原位杂交是在组织形态学背景下定位核酸靶标的分子方法。因此,它在研究和诊断病理学中具有巨大的潜在应用价值。本文试图简要回顾原位杂交方法,并阐明其作为一种新兴的临床实用技术的地位。