Rosenthal E, Qureshi S A, Chan K C, Martin R P, Skehan D J, Jordan S C, Tynan M
Department of Paediatric Cardiology, Guy's Hospital, London.
Br Heart J. 1993 Apr;69(4):347-51. doi: 10.1136/hrt.69.4.347.
To investigate the efficacy and safety of transcatheter radiofrequency-assisted valve dilatation for infants with pulmonary valve atresia and intact ventricular septum as an alternative to the use of laser heated wires.
Prospective clinical study.
Three paediatric cardiology centres.
Four children (aged 5-101 days, weight 2.8 kg) with pulmonary valve atresia and intact ventricular septum underwent percutaneous radiofrequency-assisted valve dilatation.
After delineating the atretic valve by angiography, 0.020 inch or 0.018 inch radiofrequency wires were used to perforate the atretic valve. The valve was then dilated with conventional balloon dilatation catheters up to the valve annulus diameter.
In all four cases the radiofrequency wire perforated the atretic pulmonary valve and balloon dilatation was successful. In one patient the radiofrequency wire also passed through the anterior wall of the pulmonary artery causing tamponade which required surgical repair shortly afterwards. This patient died from sepsis six days later. One patient died three weeks after the procedure from septicaemia and a paradoxical coronary embolus. Two patients were discharged after 4 and 14 days respectively.
Radiofrequency-assisted valve dilatation is a promising alternative to the recently developed laser wire technique. The major advantages are a reduction in cost and improved safety for the staff performing the procedure.
研究经导管射频辅助瓣膜扩张术治疗室间隔完整的肺动脉闭锁婴儿的疗效和安全性,以替代激光加热导丝的使用。
前瞻性临床研究。
三个儿科心脏病中心。
四名室间隔完整的肺动脉闭锁患儿(年龄5 - 101天,体重2.8千克)接受了经皮射频辅助瓣膜扩张术。
通过血管造影确定闭锁瓣膜后,使用0.020英寸或0.018英寸的射频导丝穿透闭锁瓣膜。然后用传统球囊扩张导管将瓣膜扩张至瓣环直径。
所有四例中,射频导丝均穿透了闭锁的肺动脉瓣膜,球囊扩张成功。一名患者的射频导丝还穿过了肺动脉前壁,导致心包填塞,随后不久需要进行手术修复。该患者在六天后死于败血症。一名患者在术后三周死于败血症和反常冠状动脉栓塞。两名患者分别在4天和14天后出院。
射频辅助瓣膜扩张术是最近开发的激光导丝技术的一种有前景的替代方法。主要优点是成本降低,对实施该手术的工作人员安全性提高。