Rachmiel A, Potparic Z, Jackson I T, Sugihara T, Clayman L, Topf J S, Forté R A
Institute for Craniofacial and Reconstructive Surgery, Southfield, Michigan.
Br J Plast Surg. 1993 Apr;46(3):201-7. doi: 10.1016/0007-1226(93)90169-c.
Midface osteotomy was performed on 5 young adult sheep aged 10-12 months. In 4 animals midface advancement by gradual distraction was performed using an external device; one animal served as a control. The midface was advanced by 2 mm per day for 21 days. The amount of advancement was 36 mm in the nasofrontal area and 43 mm on the lateral aspect of the maxilla. After the period of active distraction the midface was maintained with external fixation for an additional 6 weeks to allow for ossification. Radiographs were obtained immediately postoperatively, after 21 days of distraction, and at the end of the 6 week fixation period. New bone formation in the distracted area was obvious radiographically, clinically and histologically. In conclusion, midface advancement by osteotomy and gradual distraction is possible in the sheep model and may offer controlled correction of deformity, obviating the need for the bone grafting.
对5只10至12个月大的成年幼羊进行了面中部截骨术。在4只动物中,使用外部装置通过渐进性牵引进行面中部前移;1只动物作为对照。面中部每天前移2毫米,持续21天。鼻额区域前移量为36毫米,上颌外侧为43毫米。在积极牵引期后,面中部用外部固定再维持6周以促进骨化。在术后即刻、牵引21天后以及6周固定期结束时拍摄X光片。在X光片、临床和组织学上,牵引区域的新骨形成都很明显。总之,在绵羊模型中通过截骨术和渐进性牵引进行面中部前移是可行的,并且可以提供对畸形的可控矫正,从而无需植骨。