Bleyer W A
Division of Pediatrics, University of Texas, M.D. Anderson Cancer Center, Houston 77030.
Cancer. 1993 May 15;71(10 Suppl):3229-36. doi: 10.1002/1097-0142(19930515)71:10+<3229::aid-cncr2820711713>3.0.co;2-7.
National data on childhood cancer is becoming more available, but there continues to be a paucity of information.
The 1991 edition of Cancer Statistics Review was scrutinized for information on the status of pediatric cancers in the United States.
The evidence indicates that in the United States, cancer among children younger than 15 years of age is increasing in incidence. In this age group, cancer is increasing equally among whites and blacks and among girls and boys. In white children, the increase appears to be largely due to increases in acute lymphoblastic leukemia and tumors of the brain and nervous system, and not to changes in Wilms tumor, soft tissue and bone sarcomas, lymphomas and Hodgkin disease, or other common malignancies of childhood. The data in the report demonstrate that the cancer mortality rate before age 15 continues to decline steadily in both sexes and both races. Despite an increase in the incidence rate of 4% between 1973-1988, the overall cancer mortality in children younger than 15 years has decreased 38%.
The data may be interpreted to indicate that in the United States, the current cure rate of all childhood cancers combined is between 70-90%.
关于儿童癌症的全国性数据越来越容易获取,但信息仍然匮乏。
仔细查阅了1991年版的《癌症统计回顾》,以获取有关美国儿童癌症状况的信息。
有证据表明,在美国,15岁以下儿童癌症的发病率正在上升。在这个年龄组中,白人和黑人、女孩和男孩的癌症发病率都在上升。在白人儿童中,发病率上升似乎主要是由于急性淋巴细胞白血病以及脑和神经系统肿瘤的增加,而不是肾母细胞瘤、软组织和骨肉瘤、淋巴瘤和霍奇金病或其他常见儿童恶性肿瘤的变化。报告中的数据表明,15岁之前的癌症死亡率在两性和两个种族中都继续稳步下降。尽管1973年至1988年间发病率上升了4%,但15岁以下儿童的总体癌症死亡率却下降了38%。
这些数据可以解释为表明,在美国,目前所有儿童癌症的综合治愈率在70%至90%之间。