Wong J W, Cheng A Y, Binns W R, Epstein J W, Klarmann J, Perez C A
Radiation Oncology Center, Mallinckrodt Institute of Radiology, St. Louis, MO.
Int J Radiat Oncol Biol Phys. 1993 May 20;26(2):311-20. doi: 10.1016/0360-3016(93)90212-e.
We have previously reported the development of a fiber-optic fluoroscopic system for on-line imaging on radiation therapy machines with beam-stops because of space limitation. While the images were adequate for clinical purposes in most cases, an undesirable grid artifact existed and distracted visualization. The resolving power of the system, limited by the 1.6 mm x 1.6 mm dimension of the input fibers, appeared insufficient in some cases. This work identifies solutions to reduce grid artifact and to improve the resolution of the system.
In the clinical system, it was found that the scanning mechanism of the newvicon camera was deflected differently at various gantry positions because of the different orientation of the earth's magnetic field. The small image misregistration produced grid artifact during image normalization, particularly near boundaries of the fiber bundles. One approach taken to reduce magnetic field effects was to shield the camera with mu-metal. Alternatively, a charged-coupled-device camera was used instead of the newvicon camera. As for improving spatial resolution, fibers with smaller input dimension were used. A 20 cm x 20 cm high resolution fiber-optic prototype consisting of 250 x 250 fibers, each with an input dimension of 0.8 mm x 0.8 mm was constructed. Its performance was tested using several phantoms studies.
Both shielding the newvicon camera with mu-metal or replacing it with a charge-coupled-device camera reduced grid artifact. However, optimal shielding could not be made for our clinical system because of the space limitation of its housing. High contrast resolution was improved, the 30% value of the modulation transfer function occurred at 0.3 linepairs per mm for the clinical system and at 0.7 linepairs per mm for the high-resolution prototype. However, because of the larger degree of transmission non-uniformity of the prototype, it was less effective using the current setup in detecting low contrast objects.
The results are encouraging and demonstrate successful reduction of grid artifact and improvement of high contrast spatial resolution using the proposed methods. The less effective low contrast detection was related to reduced light collection efficiency due to use of prototype fibers whose productions were not closely monitored. The findings are being considered in our construction of a second generation clinical fiber-optic on-line image verification system.
由于空间限制,我们之前报道了一种用于带束流阻挡装置的放射治疗机在线成像的光纤荧光透视系统的开发。虽然在大多数情况下图像足以满足临床需求,但存在不良的网格伪影,干扰了可视化。该系统的分辨力受输入光纤1.6毫米×1.6毫米尺寸的限制,在某些情况下显得不足。这项工作确定了减少网格伪影和提高系统分辨率的解决方案。
在临床系统中,发现由于地磁场方向不同,新视康相机的扫描机制在不同的机架位置发生不同程度的偏转。在图像归一化过程中,小的图像配准误差产生了网格伪影,尤其是在纤维束边界附近。减少磁场影响的一种方法是用坡莫合金屏蔽相机。或者,使用电荷耦合器件相机代替新视康相机。至于提高空间分辨率,使用了输入尺寸更小的光纤。构建了一个20厘米×20厘米的高分辨率光纤原型,由250×250根光纤组成,每根光纤的输入尺寸为0.8毫米×0.8毫米。使用多个体模研究对其性能进行了测试。
用坡莫合金屏蔽新视康相机或用电荷耦合器件相机代替它都减少了网格伪影。然而,由于临床系统外壳的空间限制,无法对其进行最佳屏蔽。高对比度分辨率得到了提高,临床系统调制传递函数的30%值出现在每毫米0.3线对处,高分辨率原型出现在每毫米0.7线对处。然而,由于原型的透射不均匀程度较大,在当前设置下检测低对比度物体的效果较差。
结果令人鼓舞,证明了使用所提出的方法成功减少了网格伪影并提高了高对比度空间分辨率。低对比度检测效果较差与使用生产过程未得到密切监控的原型光纤导致的光收集效率降低有关。在我们构建第二代临床光纤在线图像验证系统时正在考虑这些发现。