Burke H L, Yeo R A, Delaney H D, Conner L
University of New Mexico, Albuquerque 87131.
J Clin Exp Neuropsychol. 1993 Mar;15(2):191-204. doi: 10.1080/01688639308402557.
Individual variations in anatomic cerebral asymmetries have been linked with specific neurodevelopmental processes, with patterns of cognitive ability, and with recovery from focal brain damage. The present study investigated relationships between cerebral asymmetries and recovery from aphasia. Aphasic patients (N = 25) were assessed for language recovery for 1 year poststroke, and linear measurements of cerebral asymmetries were performed on CT scans. Increasing left occipital width asymmetry was associated with faster rate of language recovery and with higher final language scores during the first year poststroke. There was, moreover, a tendency for increasing left occipital width asymmetry to be associated with less initial impairment. It is hypothesized that those aspects of neural organization conferring better premorbid language skills are the same factors conferring greater recovery of language skills and that occipital width asymmetry serves as a marker for such individual differences in neural organization.
大脑解剖结构不对称的个体差异与特定的神经发育过程、认知能力模式以及局灶性脑损伤的恢复有关。本研究调查了大脑不对称与失语症恢复之间的关系。对25名失语症患者在中风后1年进行语言恢复评估，并在CT扫描上对大脑不对称进行线性测量。左枕叶宽度不对称增加与中风后第一年语言恢复速度更快以及最终语言分数更高有关。此外，左枕叶宽度不对称增加有与初始损伤较小相关的趋势。据推测，那些赋予病前更好语言技能的神经组织方面，也是赋予语言技能更大恢复能力的相同因素，并且枕叶宽度不对称可作为神经组织中此类个体差异的一个标志。
