Perani D, Papagno C, Cappa S, Gerundini P, Fazio F
Department of Biomedical Technologies, S. Raffaele Hospital, University of Milan.
Cortex. 1988 Mar;24(1):171-8. doi: 10.1016/s0010-9452(88)80027-3.
The correlation between clinical picture, CT scan and regional cerebral blood flow (rCBF) assessed by single photon emission computerized tomography (SPECT) was investigated in two patients with crossed aphasia. The presence and degree or right hemisphere dysfunction, beyond the areas affected by CT, closely paralleled the time course of language disturbances in both patients: transient aphasia in case 1 was associated with temporary reduction of perfusion in the right hemisphere, while in case 2 persistent aphasia and apraxia were found along with severe right hemisphere hypoperfusion three year after the onset of stroke.
对两名交叉性失语患者的临床表现、CT扫描结果与通过单光子发射计算机断层扫描(SPECT)评估的局部脑血流量(rCBF)之间的相关性进行了研究。两名患者中,除CT所示受累区域外,右半球功能障碍的存在及程度与语言障碍的时间进程密切平行:病例1中的短暂性失语与右半球灌注暂时减少有关,而病例2在中风发作三年后出现持续性失语和失用症,同时伴有严重的右半球灌注不足。