Arata J, Seno A, Tada J, Wada E, Tamaki H, Tamaki M
Department of Dermatology, Okayama University Medical School, Japan.
J Am Acad Dermatol. 1993 May;28(5 Pt 2):870-3. doi: 10.1016/0190-9622(93)70121-9.
A 7-year-old girl had erythematous hyperkeratotic papules and plaques that improved in summer and recurred in winter since the age of 4 months. She had had irregular, ridge-like erythematosquamous lesions on the arms with the same seasonal variation. The lesions on the arms improved with age. Light and electron microscopic examination showed marked degeneration of keratinocytes and prominent apoptosis. Her older brother had a similar but milder dermatosis. We believe these cases may represent a variant of keratosis lichenoides chronica.
一名7岁女孩自4个月大起就出现了红斑性角化过度丘疹和斑块，夏季病情好转，冬季复发。她的手臂上有不规则的嵴状红斑鳞屑性皮损，也有相同的季节性变化。手臂上的皮损随年龄增长而改善。光镜和电镜检查显示角质形成细胞明显变性和显著凋亡。她的哥哥患有类似但较轻的皮肤病。我们认为这些病例可能代表慢性苔藓样角化病的一种变异型。
