组织工程

Tissue engineering.

作者信息

Langer R, Vacanti J P

机构信息

Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge 02319.

出版信息

Science. 1993 May 14;260(5110):920-6. doi: 10.1126/science.8493529.

DOI:10.1126/science.8493529

PMID:8493529

Abstract

The loss or failure of an organ or tissue is one of the most frequent, devastating, and costly problems in human health care. A new field, tissue engineering, applies the principles of biology and engineering to the development of functional substitutes for damaged tissue. This article discusses the foundations and challenges of this interdisciplinary field and its attempts to provide solutions to tissue creation and repair.

摘要

器官或组织的丧失或功能衰竭是人类医疗保健中最常见、最具破坏性且成本最高的问题之一。一个新的领域——组织工程学，将生物学和工程学原理应用于受损组织功能替代物的开发。本文讨论了这个跨学科领域的基础和挑战，以及它为组织创建和修复提供解决方案的尝试。