养殖水貂（Mustela vison S.）感染刚地弓形虫的实验性研究。

Experimental infection with Toxoplasma gondii in farmed mink (Mustela vison S.).

作者信息

Dietz H H, Henriksen P, Lebech M, Henriksen S A

机构信息

National Veterinary Laboratory, Dept. of Wildlife and Fur Animal Pathology, Arhus, Denmark.

出版信息

Vet Parasitol. 1993 Mar;47(1-2):1-7. doi: 10.1016/0304-4017(93)90170-r.

DOI:10.1016/0304-4017(93)90170-r

PMID:8493756

Abstract

Live Toxoplasma gondii tissue cysts (Strain 119) were administered orally to five mink (Mustela vison S.) and five mink were inoculated with a suspension of ultrasonicated Toxoplasma gondii trophozoites (RH-strain). Seroconversion was observed in all animals administered live T. gondii cysts indicating that infection was established. Likewise seroconversion was observed in three out of four animals administered ultrasonicated T. gondii trophozoites. Faecal shedding of oocysts of T. gondii was not demonstrated in any of the infected animals. Histologically chronic meningitis with calcification was seen in all animals. Cerebral T. gondii tissue cysts were detected in four animals administered live tissue cysts. The study demonstrates that mink can be experimentally infected with T. gondii, thus representing a potential infection source for man, when considering the pelting procedure.

摘要

将活的刚地弓形虫组织包囊（119株）经口接种给5只水貂（鼬属水貂），并将5只水貂接种超声破碎的刚地弓形虫滋养体悬液（RH株）。在所有接种活的刚地弓形虫包囊的动物中均观察到血清转化，表明已建立感染。同样，在接种超声破碎的刚地弓形虫滋养体的4只动物中的3只中观察到血清转化。在任何感染动物中均未发现刚地弓形虫卵囊的粪便排出。组织学检查发现所有动物均有伴有钙化的慢性脑膜炎。在接种活组织包囊的4只动物中检测到脑内刚地弓形虫组织包囊。该研究表明，水貂可通过实验感染刚地弓形虫，因此考虑到剥皮过程，水貂可能成为人类的潜在感染源。