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影响以色列直肠癌和结肠癌治疗延迟的因素。

Factors influencing delay in treatment of cancer of rectum and colon in Israel.

作者信息

Rubin M, Zer M, Dintsman M

出版信息

Isr J Med Sci. 1980 Sep-Oct;16(9-10):641-5.

PMID:7429798
Abstract

One hundred cases of malignant tumor of the colon and rectum were reviewed to determine the delay interval from onset of symptoms to operation and the factors contributing to the delay. The mean overall delay interval was 7.43 months, which is relatively long as compared with findings reported in the Western literature during recent years. In 35%, there was a mean delay of six months because of failure of the patient to consult a physician in the early stages of the disease. More serious was the finding in 62% of the patients of a doctor-caused delay of six months, because of hasty, erroneous diagnosis made without comprehensive investigation. Administrative factors caused a delay of about two months in 24% of the patients. Our findings indicated a direct correlation between duration of the delay and spread of the malignancy, with an evident tendency for a shorter delay interval among patients with carcinoma classified as Dukes' stage A. Both the public and the general physician must be educated as to the importance of early consultation and careful consideration of the patient's complaints so as to reach the correct diagnosis as soon as possible.

摘要

回顾了100例结肠和直肠癌患者,以确定从症状出现到手术的延迟时间以及导致延迟的因素。总体平均延迟时间为7.43个月,与近年来西方文献报道的结果相比相对较长。35%的患者因在疾病早期未咨询医生而平均延迟了6个月。更严重的是,62%的患者因医生未经全面检查匆忙做出错误诊断而导致延迟6个月。管理因素导致24%的患者延迟约2个月。我们的研究结果表明,延迟时间与恶性肿瘤的扩散之间存在直接关联,Dukes' A期癌患者的延迟时间明显较短。必须对公众和普通医生进行教育,使其了解早期咨询以及认真考虑患者主诉以便尽快做出正确诊断的重要性。

相似文献

1
Factors influencing delay in treatment of cancer of rectum and colon in Israel.影响以色列直肠癌和结肠癌治疗延迟的因素。
Isr J Med Sci. 1980 Sep-Oct;16(9-10):641-5.
2
Carcinoma of the colon and rectum. Delay in diagnosis.结肠直肠癌。诊断延误。
Acta Chir Scand. 1982;148(7):617-22.
3
A short diagnostic delay is more important for rectal cancer than for colonic cancer.短诊断延迟对直肠癌比对结肠癌更重要。
Eur J Surg. 1996 Nov;162(11):899-904.
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Delay in the diagnosis of colorectal cancer.结直肠癌诊断延迟。
Ann Chir Gynaecol. 1982;71(5):277-82.
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Delay in treatment of colorectal cancer: multifactorial problem.结直肠癌治疗延误:多因素问题。
World J Surg. 2003 Mar;27(3):304-8. doi: 10.1007/s00268-002-6678-9. Epub 2003 Feb 27.
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Causes of late diagnosis in cases of colorectal cancer seen in a district general hospital over a 2-year period.一家区综合医院在两年时间内诊治的结直肠癌病例中晚期诊断的原因。
Ann R Coll Surg Engl. 1998 Jul;80(4):246-8.
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Delay of treatment is associated with advanced stage of rectal cancer but not of colon cancer.治疗延迟与直肠癌的晚期阶段相关,但与结肠癌无关。
Cancer Detect Prev. 2006;30(4):341-6. doi: 10.1016/j.cdp.2006.07.001. Epub 2006 Sep 11.
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Reported symptoms, diagnostic delay and stage of colorectal cancer: a population-based study in Denmark.结直肠癌的报告症状、诊断延迟及分期:丹麦一项基于人群的研究
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Gastrointestinal carcinomas occurring in breast cancer patients.乳腺癌患者发生的胃肠道癌。
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Limited value of preoperative serum analyses of matrix metalloproteinases (MMP-2, MMP-9) and tissue inhibitors of matrix metalloproteinases (TIMP-1, TIMP-2) in colorectal cancer.术前血清基质金属蛋白酶(MMP - 2、MMP - 9)及基质金属蛋白酶组织抑制剂(TIMP - 1、TIMP - 2)分析在结直肠癌中的价值有限。
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引用本文的文献

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The effect of time before diagnosis and treatment on colorectal cancer outcomes: systematic review and dose-response meta-analysis.诊断和治疗前时间对结直肠癌结局的影响:系统评价和剂量反应荟萃分析。
Br J Cancer. 2023 Oct;129(6):993-1006. doi: 10.1038/s41416-023-02377-w. Epub 2023 Aug 1.
2
Missed opportunities to initiate endoscopic evaluation for colorectal cancer diagnosis.错失启动结直肠癌诊断内镜评估的机会。
Am J Gastroenterol. 2009 Oct;104(10):2543-54. doi: 10.1038/ajg.2009.324. Epub 2009 Jun 23.
3
Influences on pre-hospital delay in the diagnosis of colorectal cancer: a systematic review.
结直肠癌诊断中院前延迟的影响因素:一项系统综述
Br J Cancer. 2008 Jan 15;98(1):60-70. doi: 10.1038/sj.bjc.6604096. Epub 2007 Dec 4.
4
Delayed treatment for rectal cancer.直肠癌的延迟治疗。
Dis Colon Rectum. 2005 Sep;48(9):1736-41. doi: 10.1007/s10350-005-0069-x.
5
Psychological factors related to delay in consultation for cancer symptoms.与癌症症状咨询延迟相关的心理因素。
Psychooncology. 2005 May;14(5):339-50. doi: 10.1002/pon.850.