Ollikainen J, Hiekkaniemi H, Korppi M, Sarkkinen H, Heinonen K
Department of Pediatrics, Varkaus Regional Hospital, Finland.
J Pediatr. 1993 May;122(5 Pt 1):756-60. doi: 10.1016/s0022-3476(06)80022-3.
The incidence and outcome of Ureaplasma urealyticum infection were studied in 98 infants born before 34 weeks of gestational age. Infection was defined as the presence of one or more isolations of U. urealyticum in samples obtained from trachea, blood, cerebrospinal fluid, or postmortem brain or lung biopsies. Forty-seven infants were infected. Intact amniotic membranes had no protective effect against infection; intrauterine U. urealyticum infection was detected in 19 infants who were born by cesarean section with intact amniotic membranes. Respiratory distress syndrome, the need for assisted ventilation, severe respiratory insufficiency, and death were significantly more common among infected than among noninfected infants. Our results suggest that U. urealyticum infection is associated with an unfavorable short-term outcome in preterm infants.
对98名孕周小于34周出生的婴儿进行了解脲脲原体感染的发病率及转归研究。感染定义为从气管、血液、脑脊液或尸检脑或肺活检样本中分离出一株或多株解脲脲原体。47名婴儿受到感染。完整的羊膜对感染无保护作用；19名通过剖宫产出生且羊膜完整的婴儿被检测出宫内解脲脲原体感染。与未感染婴儿相比，感染婴儿中呼吸窘迫综合征、需要辅助通气、严重呼吸功能不全及死亡的情况明显更为常见。我们的结果表明，解脲脲原体感染与早产儿短期不良转归相关。
