Khurana R, Kalyanaraman K
Dis Nerv Syst. 1977 Apr;38(4):287-9.
Recent reports have emphasized the occurrence of a myopathy in chronic alcoholism associated with hypokalemia. This report of hypokalemic myopathy in a chronic alcoholic, emphasizes the primary myopathic nature of the condition and attributes it to a possible non-specific effect of the hypokalemia on skeletal muscle. It is pointed out, that histological and histochemical changes of muscle in this type of myopathy are indistinguishable from other types of hypokalemic myopathies like periodic paralysis. It is conjectured that in alcoholic myopathy, the underlying disorder might be related to a primary disturbance of potassium metabolism, though in most cases, serum potassium is normal. It is likely that studies aimed at studying total body potassium content and turnover in alcoholic myopathy would help in understanding its pathogenesis and possible relationship to disturbed potassium metabolism.
近期报告强调了慢性酒精中毒伴低钾血症时会出现肌病。本文报告了一例慢性酒精中毒患者的低钾性肌病，强调了该病的原发性肌病本质，并将其归因于低钾血症对骨骼肌可能产生的非特异性影响。文中指出，这类肌病中肌肉的组织学和组织化学变化与其他类型的低钾性肌病（如周期性瘫痪）并无区别。据推测，在酒精性肌病中，潜在疾病可能与钾代谢的原发性紊乱有关，尽管在大多数情况下血清钾是正常的。旨在研究酒精性肌病中全身钾含量和周转情况的研究，可能有助于理解其发病机制以及与钾代谢紊乱的可能关系。
