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[一名合成代谢类固醇使用者的扩张型心肌病]

[Dilated cardiomyopathy in a user of anabolic steroids].

作者信息

Schollert P V, Bendixen P M

机构信息

Medicinsk afdeling, Haderslev Sygehus.

出版信息

Ugeskr Laeger. 1993 Apr 19;155(16):1217-8.

PMID:8497958
Abstract

A case is described in which a 32-year old male body-builder was admitted with signs of cardiac incompensation after using anabolic steroids (AS) in large amounts for three weeks before admittance. Echo-cardiography showed a dilated left ventricle with decreased systolic function and electrocardiography showed atrial fibrillation. Response to treatment was good and he was discharged to further out-patient treatment. After nine weeks he was admitted with severe cardiac incompensation. There was no response to treatment and he died after three days. At autopsy the heart weighted 527 grams and was diffusely dilated. There were no signs of infarction. Microscopy showed scattered lymphocyte infiltrates consistent with dilated cardiomyopathy, possibly caused by myocarditis. There were no signs of bacterial infection, the patient was a non-alcoholic and no other known cause of myocarditis was shown. We conclude that the patient died from toxic myocarditis with dilated cardiomyopathy caused by AS.

摘要

本文描述了一例病例,一名32岁的男性健美运动员在入院前三周大量使用合成代谢类固醇(AS)后,因心脏代偿失调症状入院。超声心动图显示左心室扩张,收缩功能下降,心电图显示房颤。治疗反应良好,他出院接受进一步的门诊治疗。九周后,他因严重的心脏代偿失调再次入院。治疗无效,三天后死亡。尸检时心脏重527克,弥漫性扩张。没有梗死迹象。显微镜检查显示散在的淋巴细胞浸润,符合扩张型心肌病,可能由心肌炎引起。没有细菌感染迹象,患者不饮酒,也未显示其他已知的心肌炎病因。我们得出结论,该患者死于AS引起的中毒性心肌炎伴扩张型心肌病。

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