University of South Florida, Tampa, FL, USA.
J Card Fail. 2009 Aug;15(6):496-500. doi: 10.1016/j.cardfail.2008.12.014. Epub 2009 Feb 10.
Athletes use androgenic-anabolic steroids to increase strength and muscle mass. Several case reports suggest that it may lead to dilated cardiomyopathy.
We report a case of a 41-year-old bodybuilder with severe systolic dysfunction and Class IV heart failure despite maximal medical therapy. He used anabolic steroids and insulin growth factor, and did not have any other risk factors for cardiomyopathy. We briefly review the literature and summarize other reported cases with similar scenarios. In most of them cardiomyopathy was at least partially reversible after discontinuation of anabolics.
Abuse of anabolic steroids may be an uncommon cause of cardiomyopathy in young and otherwise healthy individuals.
运动员使用雄激素和合成代谢类固醇来提高力量和肌肉质量。有几项病例报告表明,它可能导致扩张型心肌病。
我们报告了一例 41 岁的健美运动员,尽管接受了最大程度的药物治疗,但仍存在严重的收缩功能障碍和 IV 级心力衰竭。他使用了合成代谢类固醇和胰岛素生长因子,并且没有任何其他导致心肌病的危险因素。我们简要回顾了文献并总结了其他类似情况下报告的病例。在大多数情况下,停用合成代谢类固醇后,心肌病至少部分可逆。
滥用合成代谢类固醇可能是年轻且健康的个体发生心肌病的一种不常见原因。