Ghidini A, Sepulveda W, Lockwood C J, Romero R
Department of Obstetrics, Gynecology, and Reproductive Sciences, Mount Sinai School of Medicine, New York, New York.
Am J Obstet Gynecol. 1993 May;168(5):1339-44. doi: 10.1016/s0002-9378(11)90761-3.
To examine the incidence and significance of complications related to percutaneous fetal blood sampling, we reviewed all the articles published in the English literature on this procedure. Risks of complications and adverse outcomes depend mainly on the gestational age at the time of the procedure, the operator's experience, and the indication for the procedure. To determine the incidence of fetal losses, we pooled the data from series with > 100 cases. After exclusion of cases where some fetal pathologic condition was present, we determined the incidence of adverse outcomes in a low-risk population. In this population fetal blood sampling performed by an experienced operator carries about a 1.4% risk of fetal loss before 28 weeks' gestation and a 1.4% risk of perinatal death (after 28 weeks).
为了研究经皮胎儿采血相关并发症的发生率及意义，我们回顾了英文文献中发表的关于该操作的所有文章。并发症和不良结局的风险主要取决于操作时的孕周、操作者的经验以及操作的适应证。为了确定胎儿丢失的发生率，我们汇总了病例数超过100例的系列研究数据。在排除存在某些胎儿病理状况的病例后，我们确定了低风险人群中不良结局的发生率。在该人群中，由经验丰富的操作者进行的胎儿采血在妊娠28周前导致胎儿丢失的风险约为1.4%，围产期死亡风险（28周后）为1.4%。
