边缘型人格障碍的神经行为研究。
Neurobehavioral study of borderline personality disorder.
作者信息
van Reekum R, Conway C A, Gansler D, White R, Bachman D L
机构信息
McMaster University, Hamilton, Ontario, Canada.
出版信息
J Psychiatry Neurosci. 1993 May;18(3):121-9.
The existence of an "organic" subgroup of borderline personality disorder (BPD) has been postulated. This report is of a case-controlled, chart-review study of BPD. The control sample consisted of patients with a variety of psychiatric diagnoses. The study found that 81% of the patients with BPD and 22% of the control patients had a history of brain injury, either developmental (44%), acquired (58%) or both. Furthermore, there was a positive correlation between the summed number of developmental and acquired brain injuries and the score on the retro-Diagnostic Interview for Borderline. A pilot neuropsychological study showed that seven of nine subjects with BPD had evidence of frontal system dysfunction. These results help to support the hypothesized existence of an organic BPD subgroup.
边缘型人格障碍（BPD）的一个“器质性”亚组的存在已被提出。本报告是一项关于BPD的病例对照、病历回顾研究。对照样本由患有各种精神疾病诊断的患者组成。研究发现，81%的BPD患者和22%的对照患者有脑损伤史，包括发育性脑损伤（44%）、后天性脑损伤（58%）或两者皆有。此外，发育性和后天性脑损伤的总数与边缘型人格障碍回顾性诊断访谈的得分之间存在正相关。一项初步的神经心理学研究表明，9名BPD受试者中有7名有额叶系统功能障碍的证据。这些结果有助于支持假设的器质性BPD亚组的存在。
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