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白细胞介素8受体(IL8R)A和B的基因定位于人染色体2q35带。

Assignment of genes for interleukin-8 receptors (IL8R) A and B to human chromosome band 2q35.

作者信息

Lloyd A, Modi W, Sprenger H, Cevario S, Oppenheim J, Kelvin D

机构信息

Laboratory of Molecular Immunoregulation, National Cancer Institute, Frederick, MD 21702.

出版信息

Cytogenet Cell Genet. 1993;63(4):238-40. doi: 10.1159/000133541.

DOI:10.1159/000133541
PMID:8500355
Abstract

The human genes encoding the interleukin 8 receptors type A and B were assigned to chromosome 2 by polymerase chain reaction amplification and by Southern analysis of a panel of human x rodent somatic cell hybrid DNAs. The IL8R genes were further localized by in situ hybridization to band 2q35.

摘要

通过聚合酶链反应扩增以及对一组人-啮齿动物体细胞杂交DNA进行Southern分析,编码白细胞介素8 A型和B型受体的人类基因被定位于2号染色体。通过原位杂交,白细胞介素8受体(IL8R)基因被进一步定位到2q35带。

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