Catts S V, McConaghy N, Ward P B, Fox A M, Hadzi-Pavlovic D
Division of Psychiatry, Prince of Wales Hospital, Randwick, Australia.
J Nerv Ment Dis. 1993 May;181(5):298-302. doi: 10.1097/00005053-199305000-00004.
Romney (J. Nerv. Ment. Dis. 178:481-486, 1990) performed a meta-analysis of studies examining psychometrically assessed "thought disorder" in the relatives of schizophrenics. He concluded that thought disorder was more prevalent in the relatives of schizophrenics than control subjects. The present review focuses on only those studies that measured "allusive thinking" using the Lovibond-Rapaport Object Sorting Test in parents of schizophrenics. Even when the meta-analysis included this more limited number of studies, it demonstrated that the parents of schizophrenics were 2.42 times more likely to obtain high scores on the Object Sorting Test, confirming replication of the original McConaghy (J. Neurol. Neurosurg. Psychiatry 22:243-246, 1959) finding. This effect remained significant when the original study was excluded from the meta-analysis. The predictive strength of parental Object Sorting Test score as a familial risk factor for the development of schizophrenia is discussed.
罗姆尼（《神经与精神疾病杂志》178:481 - 486，1990年）对研究精神分裂症患者亲属中经心理测量评估的“思维紊乱”的研究进行了荟萃分析。他得出结论，思维紊乱在精神分裂症患者的亲属中比在对照对象中更为普遍。本综述仅关注那些在精神分裂症患者的父母中使用洛维邦德 - 拉帕波特物体分类测验测量“隐喻思维”的研究。即使荟萃分析纳入的研究数量更为有限，结果也表明，精神分裂症患者的父母在物体分类测验中获得高分的可能性是其他人的2.42倍，这证实了最初麦康纳吉（《神经病学、神经外科学与精神病学杂志》22:243 - 246，1959年）研究结果的重复性。当将最初的研究排除在荟萃分析之外时，这一效应仍然显著。本文还讨论了父母物体分类测验得分作为精神分裂症发病家族风险因素的预测强度。
