Callahan L A, Saccuzzo D P
J Nerv Ment Dis. 1986 Apr;174(4):240-2. doi: 10.1097/00005053-198604000-00007.
The first-degree blood relatives of schizophrenics were compared to a matched control group on a psychometrically matched test of responsiveness to associative intrusions. The groups differed on the subtest containing an associative alternative but not on the equally difficult subtest free of associative distractors. Results were consistent with the hypothesis that an overresponsiveness to associative distractors, well documented in schizophrenics, may also be a characteristic of their nondisturbed first degree blood relatives. The possible existence of cognitive markers in the relatives of schizophrenic patients that might indicate familial psychopathology was supported. Limitations of the present preliminary findings, as well as the case for additional investigation of the cognitive behavior of the first-degree relatives of schizophrenics, are discussed.
在一项关于对联想性干扰反应性的心理测量匹配测试中，将精神分裂症患者的一级血亲与匹配的对照组进行了比较。在包含联想性替代选项的子测试中，两组存在差异，但在同样难度且无联想性干扰项的子测试中，两组没有差异。结果与以下假设一致：精神分裂症患者中充分记录的对联想性干扰的过度反应，也可能是其未患病的一级血亲的特征。这支持了精神分裂症患者亲属中可能存在认知标记，这些标记可能表明家族性精神病理学的观点。讨论了当前初步研究结果的局限性，以及对精神分裂症患者一级亲属的认知行为进行进一步研究的理由。
