Robert S, Zarowitz B J, Hyzy R, Eichenhorn M, Peterson E L, Popovich J
Department of Pharmacy, Henry Ford Hospital, Detroit, MI 48202.
Am J Clin Nutr. 1993 Jun;57(6):840-4. doi: 10.1093/ajcn/57.6.840.
The objective of this study was to assess the utility of bioelectrical impedance analysis (BIA) in determining nutritional status in critically ill patients in the intensive care unit (ICU). Data were collected prospectively in 33 mechanically ventilated medical and surgical ICU patients requiring nutrition as part of their care. BIA, with subsequent calculation of body-composition indexes, was performed every other day for the duration of ICU stay. Body cell mass (BCM) changes correlated with energy and protein intakes (r2 = 0.87, P < 0.001 and r2 = 0.67, P < 0.001, respectively). Maintenance of BCM was achieved by a daily provision of 125.5 kJ.kg-1.d-1 (30 kcal.kg-1.d-1) and 1.5 g protein/kg whereas greater intakes allowed restoration of BCM. The mean ratios of exchangeable sodium to potassium (Nae:Ke) improved only in patients achieving positive nitrogen balance (P = 0.013). Body-composition changes determined by BIA represent a feasible adjunctive method for evaluating and monitoring nutritional status in ICU patients.
本研究的目的是评估生物电阻抗分析(BIA)在确定重症监护病房(ICU)危重症患者营养状况方面的效用。前瞻性收集了33例需要营养支持作为其治疗一部分的机械通气内科和外科ICU患者的数据。在患者入住ICU期间,每隔一天进行一次BIA,并随后计算身体成分指数。身体细胞质量(BCM)变化与能量和蛋白质摄入量相关(r2分别为0.87,P < 0.001和r2为0.67,P < 0.001)。通过每日提供125.5 kJ·kg-1·d-1(30 kcal·kg-1·d-1)和1.5 g蛋白质/kg可维持BCM;而摄入量增加则可使BCM恢复。仅在实现正氮平衡的患者中,可交换钠与钾的平均比率(Nae:Ke)有所改善(P = 0.013)。由BIA确定的身体成分变化是评估和监测ICU患者营养状况的一种可行的辅助方法。