天花疫苗效力的改变对机体免疫反应性的影响。
The influence of modifications in the potency of smallpox vaccines on the immunological reactivity of the organism.
作者信息
Topciu V, Giurcă A, Voiculescu D, Moldovan E, Plavoşin L
出版信息
Virologie. 1977 Jan-Mar;28(1):63-6.
The possible influence of shipment and storage conditions upon the potency of smallpox vaccines was investigated by testing the direct effect of vaccine potency on the type of cutaneous reaction and on the level of serum antibodies. Vaccine no. 1--freshly prepared, shipped and stored at +4 degrees C--proved to be more potent than vaccine no. 2, at the limit of its efficiency, shipped and maintained under usual conditions. To maintain the initial potency of smallpox vaccines it is recommended either to improve the shipment and storage conditions, or to use a lyophilized vaccine.
通过测试疫苗效力对皮肤反应类型和血清抗体水平的直接影响，研究了运输和储存条件对天花疫苗效力可能产生的影响。1号疫苗——新制备的，在4摄氏度下运输和储存——被证明比2号疫苗效力更强，2号疫苗在其效力极限时，在通常条件下运输和保存。为保持天花疫苗的初始效力，建议要么改善运输和储存条件，要么使用冻干疫苗。
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