Hautmann R E, Miller K, Steiner U, Wenderoth U
Department of Urology, Faculty of Medicine, University of Ulm, Germany.
J Urol. 1993 Jul;150(1):40-5. doi: 10.1016/s0022-5347(17)35392-2.
Between April 1986 and April 1992, 211 consecutive men underwent lower urinary tract reconstruction by means of the ileal neobladder. There have been 5 perioperative deaths for an operative mortality rate of 2.4%. The early complication rate for issues not directly related to the neobladder was 7.5% compared to a 6.5% directly neobladder-related early reoperation rate. Neobladder-related late complications requiring rehospitalization or reoperation have been acceptable, including ileus (2%), abscess (1%), colon-reservoir fistula (1.5%), hydronephrosis (1%), ureteral stenosis (3.6%) and transurethral incision of the urethroileal anastomosis (7%). Overall, only 29.3% of our patients had no complication, whereas 32% suffered significant problems requiring rehospitalization or reoperation. The remainder of the patients suffered minor but not negligible problems. Excellent continence was achieved early and increased with time: 85% of the patients were perfectly dry night and day by 3 years. At this date only 5.5% of the patients had nighttime incontinence, while 6% wear protection for occasional accidents. Intermittent catheterization is necessary in 3.5% of the patients because of the inability to void or maintain a post-void residual volume of less than 100 ml. Despite the fact that some price must be paid for excellent continence, natural voiding and undisturbed body image, the ileal neobladder continues to be our procedure of choice for male patients after cystectomy provided there is no evidence of prostatic or urethral involvement. Our results should stimulate earlier patient and physician acceptance of cystectomy.
1986年4月至1992年4月期间,连续211名男性通过回肠新膀胱进行了下尿路重建。围手术期死亡5例,手术死亡率为2.4%。与新膀胱无直接关系的早期并发症发生率为7.5%,而与新膀胱直接相关的早期再次手术率为6.5%。需要再次住院或再次手术的与新膀胱相关的晚期并发症是可以接受的,包括肠梗阻(2%)、脓肿(1%)、结肠贮尿囊瘘(1.5%)、肾积水(1%)、输尿管狭窄(3.6%)和经尿道切开尿道回肠吻合口(7%)。总体而言,我们的患者中只有29.3%没有并发症,而32%患有需要再次住院或再次手术的严重问题。其余患者有轻微但不可忽视的问题。早期即实现了良好的控尿,且随着时间推移有所增加:到3年时,85%的患者日夜完全干爽。此时,只有5.5%的患者夜间失禁,而6%的患者因偶尔失禁而使用防护用品。由于无法排尿或排尿后残余尿量无法维持在100 ml以下,3.5%的患者需要间歇性导尿。尽管为了实现良好的控尿、自然排尿和不受干扰的身体形象必须付出一些代价,但只要没有前列腺或尿道受累的证据,回肠新膀胱仍然是我们对男性患者膀胱切除术后的首选手术方式。我们 的结果应促使患者和医生更早地接受膀胱切除术。