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[一名老年男性因肠道出血引发的人细小病毒B19所致再生障碍危象]

[Human parvovirus B19-induced aplastic crisis in an elderly man with intestinal hemorrhage].

作者信息

Kamoshita M, Ohtani K, Hasegawa Y, Satoh Y, Kozima H, Shibuya A, Ninomiya H, Nagasawa T, Matsunaga Y, Abe T

机构信息

Division of Hematology, University of Tsukuba.

出版信息

Rinsho Ketsueki. 1993 Apr;34(4):493-5.

PMID:8510339
Abstract

An elderly man with an intestinal hemorrhage from bowel diverticulosis developed human parvovirus B19-induced aplastic crisis. A 71-year-old man noticed occasional tarry stools and at the same time showed fever, arthralgia and severe anemia. Blood counts revealed Hgb 5.3g/dl, reticulocytes 0%, and WBC 1,900/microliters. Bone marrow examination showed hypocellular marrow with rare erythroid precursors (4.8%). A few giant proerythroblasts were found in the bone marrow smears. A diagnosis of parvovirus B19 infection was made because of detection of B19-specific IgM and IgG antibodies. Parvovirus B19 infection should be carefully checked for in patients with hemorrhage as well as those with hemolysis.

摘要

一名患有肠憩室病并伴有肠道出血的老年男性发生了人细小病毒B19诱导的再生障碍危象。一名71岁男性注意到偶尔出现柏油样便,同时伴有发热、关节痛和严重贫血。血细胞计数显示血红蛋白5.3g/dl,网织红细胞0%,白细胞1900/微升。骨髓检查显示骨髓细胞减少,红系前体细胞罕见(4.8%)。骨髓涂片发现少数巨大早幼红细胞。由于检测到B19特异性IgM和IgG抗体,诊断为人细小病毒B19感染。对于出血患者以及溶血患者,应仔细检查是否感染人细小病毒B19。

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