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[上颌骨软骨肉瘤。一例临床病例报告]

[Chondrosarcoma of the maxilla. A clinical case report].

作者信息

Berrone S, Gallesio C, Anglesio R

机构信息

Istituto di Clinica Odontostomatologica, Università degli Studi di Torino.

出版信息

Minerva Stomatol. 1993 Jan-Feb;42(1-2):49-56.

PMID:8510619
Abstract

Chondrosarcoma are malignant tumour originating in cartilaginous cells which tend to preserve their essentially cartilaginous nature throughout their evolution. They are rare at the level of the maxilla and mandibular. When localized in facial bone, chondrosarcoma follow a more aggressive pattern compared to those localized in long bones. They mainly affect individuals aged between 30 and 60 and show no sexual preference. In the majority of cases, chondrosarcoma have a relatively slow rate of growth. The only valid treatment is radical surgical removal. In overall terms, the prognosis in these patients is not good since the 5-year survival rate is less than 40%. During the period 1980-1992 only 5 cases of chondrosarcoma were diagnosed by the Division of Maxillo-Facial Surgery of the University of Turin. The authors considered it worthwhile to report the last case observed in a premaxillary localization given the advanced age of onset and the typical course of the pathology and treatment received. CASE REPORT. A male 83-year-old patient was referred to use due to a slow growing neoformation in the premaxillary region which had appeared approximately 5-6 months earlier. The patient had previously undergone the avulsion of residual upper teeth due to suspected "toothache". The neoformation filled the premaxilla, deforming the anterior middle portion of the palate and spreading towards the floor of the anterior nasal cavity. The gingiva of the upper alveolar crest presented ulceration with irregular edges and sanious bottom. On palpation the consistency was hard-ligneous and swelling, in continuity with the bone, was slightly painful. Incisional biopsy enabled the diagnosis of chondrosarcoma to be confirmed.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

软骨肉瘤是起源于软骨细胞的恶性肿瘤,在其整个发展过程中往往保持其基本的软骨性质。它们在上颌骨和下颌骨部位较为罕见。当位于面骨时,软骨肉瘤比位于长骨的软骨肉瘤具有更具侵袭性的生长方式。它们主要影响30至60岁的个体,无性别差异。在大多数情况下,软骨肉瘤的生长速度相对较慢。唯一有效的治疗方法是根治性手术切除。总体而言,这些患者的预后不佳,因为5年生存率低于40%。在1980年至1992年期间,都灵大学颌面外科仅诊断出5例软骨肉瘤。鉴于发病年龄较大以及所接受的病理和治疗的典型过程,作者认为报告在前上颌骨部位观察到的最后一例病例是值得的。病例报告。一名83岁男性患者因大约5 - 6个月前出现在前上颌骨区域的缓慢生长的新生物而前来就诊。该患者此前因疑似“牙痛”拔除了残留的上牙。新生物充满前上颌骨,使腭部前中部变形并向前鼻腔底部蔓延。上牙槽嵴的牙龈出现边缘不规则且底部有脓血的溃疡。触诊时质地硬如骨,肿胀,与骨相连,有轻微压痛。切开活检确诊为软骨肉瘤。(摘要截断于250字)

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