甲型流感病毒/阿拉木图/1417/84（H1N1血清变种HSW1N1）血凝素基因全长DNA拷贝的合成、克隆及一级结构测定

[Synthesis, cloning, and determination of the primary structure of a full-length DNA copy of the gene for influenza A/Alma-Ata/1417/84 virus (H1N1-serovariant HSW1N1) hemagglutinin].

作者信息

Beklemishev A B, Nazarova L M, Filimonov N G, Blinov V M, Grinev A A, Chuvakova Z K, Kim E V, Mukazhanova G N

出版信息

Mol Gen Mikrobiol Virusol. 1993 Jan-Feb(1):24-7.

Abstract

The full-length copy of the hemagglutinin gene RNA of the influenza virus A/Alma Ata/1417/84 (Hsw1 N1-serovariant) has been synthesized and cloned on Escherichia coli plasmid pBR327. The complete nucleotide sequence of the cloned DNA copy was determined by the Maxam-Gilbert procedure. The predicted amino acid, sequence of HA1 hemagglutinin subunit was compared with the sequences of HA1 subunits from other H1N1-subtype influenza virus strains. It has been found that the structure of the HA1-subunit of the studied strain is most similar to the structure of the identical region of the A/New Jersey/18/76 hemagglutinin.

摘要

甲型流感病毒A/阿拉木图/1417/84（Hsw1 N1血清变种）血凝素基因RNA的全长拷贝已被合成并克隆到大肠杆菌质粒pBR327上。通过马克萨姆-吉尔伯特法测定了克隆DNA拷贝的完整核苷酸序列。将预测的HA1血凝素亚基的氨基酸序列与其他H1N1亚型流感病毒株的HA1亚基序列进行了比较。已发现所研究毒株的HA1亚基结构与A/新泽西/18/76血凝素相同区域的结构最为相似。

相似文献

1

[Synthesis, cloning, and determination of the primary structure of a full-length DNA copy of the gene for influenza A/Alma-Ata/1417/84 virus (H1N1-serovariant HSW1N1) hemagglutinin].甲型流感病毒/阿拉木图/1417/84（H1N1血清变种HSW1N1）血凝素基因全长DNA拷贝的合成、克隆及一级结构测定

Mol Gen Mikrobiol Virusol. 1993 Jan-Feb(1):24-7.

2

[Synthesis of a full-length DNA copy of the hemagglutinin gene of the the influenza virus A H1N1 subtype, its cloning and primary structure].[甲型H1N1流感病毒血凝素基因全长DNA拷贝的合成、克隆及一级结构]

Bioorg Khim. 1984 Nov;10(11):1535-43.

3

[Primary structure of the full-size DNA copy of the hemagglutinin gene of influenza virus A/Kiev/59/79 (H1N1)].甲型流感病毒/基辅/59/79（H1N1）血凝素基因全长DNA拷贝的一级结构

Bioorg Khim. 1986 Mar;12(3):375-81.

4

[Synthesis, cloning and determination of the primary structure of a full-size DNA copy of the neuraminidase gene from influenza virus type A subtype H1N1].甲型H1N1流感病毒神经氨酸酶基因全长DNA拷贝的合成、克隆及一级结构测定

Bioorg Khim. 1985 May;11(5):628-35.

5

[An analysis of the amino acid sequence of the heavy subunit of the hemagglutinin in influenza virus A/Alma-Ata/1417/84].[甲型流感病毒/阿拉木图/1417/84血凝素重链亚基氨基酸序列分析]

Vopr Virusol. 1994 Jan-Feb;39(1):30-4.

6

[Primary structure of fragment 7 of the influenza virus A/USSR/90/77(H1N1) RNA].[甲型流感病毒A/苏联/90/77（H1N1）RNA片段7的一级结构]

Bioorg Khim. 1985 Aug;11(8):1080-6.

7

[Primary structure of the full-size DNA copy of the influenza virus A/Kiev/59/79 (H1N1) PB1 gene protein].[甲型流感病毒A/基辅/59/79（H1N1）PB1基因蛋白全尺寸DNA拷贝的一级结构]

Bioorg Khim. 1987 Sep;13(9):1170-5.

8

[Primary structure of the full-length DNA copy of the influenza virus A/Kiev/59/79 (H1N1) PB2 gene].[甲型流感病毒A/基辅/59/79（H1N1）PB2基因全长DNA拷贝的一级结构]

Bioorg Khim. 1987 Jul;13(7):915-20.

9

[Synthesis, cloning and determination of the primary structure of a full-size DNA copy of the NP protein gene from influenza virus type A].[A 型流感病毒 NP 蛋白基因全长 DNA 拷贝的合成、克隆及一级结构测定]

Bioorg Khim. 1985 May;11(5):636-40.

10

[Evolution of the hemagglutinin gene of influenza A virus H1N1-subtype (1977-1983].甲型流感病毒H1N1亚型血凝素基因的演变（1977 - 1983年）

Mol Gen Mikrobiol Virusol. 1986 Nov(11):3-7.

引用本文的文献

1

The haemagglutinin gene, but not the neuraminidase gene, of 'Spanish flu' was a recombinant.“西班牙流感”的血凝素基因是重组基因，而神经氨酸酶基因不是。

Philos Trans R Soc Lond B Biol Sci. 2001 Dec 29;356(1416):1845-55. doi: 10.1098/rstb.2001.0998.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。