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[八旬老人的冠状动脉血管成形术]

[Coronary angioplasty in octogenarians].

作者信息

Camenzind E, Meier B, Urban P, Favre Dorsaz P, Dosso J F, Rutishauser W

机构信息

Centre de cardiologie, Hôpital cantonal universitaire de Genève.

出版信息

Schweiz Med Wochenschr. 1993 May 15;123(19):970-6.

PMID:8511527
Abstract

Coronary balloon angioplasty was performed on 33 lesions during 28 procedures in 23 octogenarians (median age 83, range 80 to 87 years) between January 1989 and December 1991. 96% of the patients had grade III-IV angina pectoris. The median left ventricular ejection fraction was 64% (range: 38-85%). Single vessel coronary artery disease was present in 43% and multivessel coronary artery disease in 57%. Angioplasty was performed on 1 vessel in 85% of the procedures and on 2 vessels in 15%. Primary angiographic success was 97% for 33 attempted lesions with one failure to recanalize an old occlusion. One patient underwent emergency intracoronary stent implantation after failed angioplasty. None underwent emergency coronary bypass surgery. One patient (4%) had a myocardial infarction and 2 patients (7%) died during hospitalization, the first because of abrupt vessel closure during angioplasty, the second due to acute retroperitoneal bleeding on the 8th day post-angioplasty while fully anticoagulated for an intracoronary stent. Follow-up (median 17, range 8 to 39 months) was obtained for all patients. Out of the 21 patients with primary angioplastic success, 3 (14%) had died (1 cardiac and 2 non-cardiac). At 1 year actuarial survival was 86%, and survival free from myocardial infarction or coronary bypass surgery was 81%. Further angioplasty for either restenosis or another lesion was performed in 5 patients (24%). These results confirm that coronary angioplasty is an effective means of controlling anginal symptoms in a selected group of severely symptomatic octogenarians. However, when complications do occur they are linked to a significant mortality rate.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

1989年1月至1991年12月期间,对23名八旬老人(年龄中位数83岁,范围80至87岁)的28例手术中的33处病变进行了冠状动脉球囊血管成形术。96%的患者患有III-IV级心绞痛。左心室射血分数中位数为64%(范围:38-85%)。43%的患者存在单支冠状动脉疾病,57%的患者存在多支冠状动脉疾病。85%的手术对1支血管进行了血管成形术,15%的手术对2支血管进行了血管成形术。33处尝试治疗的病变中,初次血管造影成功率为97%,1处陈旧性闭塞未能再通。1例患者血管成形术失败后接受了急诊冠状动脉内支架植入术。无人接受急诊冠状动脉搭桥手术。1例患者(4%)发生心肌梗死,2例患者(7%)在住院期间死亡,第1例死于血管成形术期间血管突然闭塞,第2例死于血管成形术后第8天急性腹膜后出血,当时因冠状动脉内支架而充分抗凝。对所有患者进行了随访(中位数17个月,范围8至39个月)。在21例初次血管成形术成功的患者中,3例(14%)死亡(1例心脏原因,2例非心脏原因)。1年时的精算生存率为86%,无心肌梗死或冠状动脉搭桥手术的生存率为81%。5例患者(24%)因再狭窄或其他病变接受了进一步的血管成形术。这些结果证实,冠状动脉血管成形术是控制一组有严重症状的八旬老人心绞痛症状的有效手段。然而,当并发症确实发生时,它们与显著的死亡率相关。(摘要截取自250字)

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