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巴雷特食管炎合并食管腺癌和类癌：肠嗜铬样细胞在食管恶性肿瘤中的潜在作用

Combined oesophageal adenocarcinoma and carcinoid in Barrett's oesophagitis: potential role of enterochromaffin-like cells in oesophageal malignancy.

作者信息

Cary N R, Barron D J, McGoldrick J P, Wells F C

机构信息

Department of Pathology, Papworth Hospital, Everard, Cambridge.

出版信息

Thorax. 1993 Apr;48(4):404-5. doi: 10.1136/thx.48.4.404.

DOI:10.1136/thx.48.4.404
PMID:8511743
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC464444/
Abstract

A case of combined adenocarcinoma and carcinoid tumour which occurred in a patient with a Barrett's oesophagus is presented. Its significance is discussed in relation to the potential role of enterochromaffin-like cells in the development of oesophageal malignancy, and the possibility is raised that long term treatment with omeprazole, commonly used in this condition, could promote this.

摘要

本文报告了一例发生在患有巴雷特食管患者身上的腺癌和类癌合并病例。结合嗜铬样细胞在食管恶性肿瘤发生中的潜在作用，对该病例的意义进行了讨论，并提出了在这种情况下常用的奥美拉唑长期治疗可能会促进肿瘤发生的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20e9/464444/88e6d2b87a9f/thorax00376-0101-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20e9/464444/958250fb4c19/thorax00376-0100-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20e9/464444/88e6d2b87a9f/thorax00376-0101-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20e9/464444/958250fb4c19/thorax00376-0100-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20e9/464444/88e6d2b87a9f/thorax00376-0101-a.jpg

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本文引用的文献

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Barrett's metaplasia and adenocarcinoma of the esophagus and gastroesophageal junction.巴雷特化生以及食管和胃食管交界腺癌
Hum Pathol. 1983 Jan;14(1):42-61. doi: 10.1016/s0046-8177(83)80045-8.
2
Composite gastric carcinoid and adenocarcinoma.复合性胃类癌和腺癌。
Histopathology. 1984 May;8(3):529-36. doi: 10.1111/j.1365-2559.1984.tb02362.x.
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Carcinoid tumour of the oesophagus: report of a case.食管类癌肿瘤：一例报告。
Clin J Gastroenterol. 2019 Dec;12(6):534-538. doi: 10.1007/s12328-019-00995-7. Epub 2019 May 27.
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Perianal Goblet Cell Carcinoid With Pagetoid Spread.伴有派杰样扩散的肛周杯状细胞类癌
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Rare Synchronous Alliance of Three Commonly Occurring Gastrointestinal Tumors-a Case Report and Brief Review of Literature.罕见的三种常见胃肠道肿瘤同步联合——一例报告及文献简要综述
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Early precursor of mixed endocrine-exocrine tumors of the gastrointestinal tract: histologic and molecular correlations.胃肠道混合性内分泌-外分泌肿瘤的早期前体：组织学与分子相关性
Ochsner J. 2015 Spring;15(1):97-101.
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Mixed Adenoneuroendocrine Carcinomas (MANECs) of the Gastrointestinal Tract: An Update.胃肠道混合性腺神经内分泌癌（MANEC）：最新进展。
Cancers (Basel). 2012 Jan 16;4(1):11-30. doi: 10.3390/cancers4010011.
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Endoscopic mucosal resection of an oesophageal carcinoid tumour.食管类癌肿瘤的内镜下黏膜切除术。
BMJ Case Rep. 2013 Apr 3;2013:bcr2012008288. doi: 10.1136/bcr-2012-008288.
10
Immunohistochemical study of neuroendocrine cells at the gastric cardia mucosa.胃贲门黏膜神经内分泌细胞的免疫组织化学研究
J Clin Pathol. 2002 Oct;55(10):767-9. doi: 10.1136/jcp.55.10.767.
Scott Med J. 1980 Jul;25(3):245-9. doi: 10.1177/003693308002500313.
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Malignant carcinoid of the stomach and distal esophagus. Review of the literature and a case report.胃和食管远端的恶性类癌。文献综述及病例报告。
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Cancer. 1979 Nov;44(5):1853-9. doi: 10.1002/1097-0142(197911)44:5<1853::aid-cncr2820440544>3.0.co;2-d.