Sulak P J, Haney A F
Department of Obstetrics and Gynecology, Texas A&M University College of Medicine, Temple.
Am J Obstet Gynecol. 1993 Jun;168(6 Pt 2):2042-8. doi: 10.1016/s0002-9378(12)90947-3.
The highest percentages of unintended pregnancies and the largest increases in births reported in the United States in recent years were in adolescents and in women more than 35 years of age. Increasing numbers of these women will require contraception to avoid unintended pregnancy. In adolescents the combined oral contraceptive agents protect fertility indirectly and exert favorable actions on menstrual dysfunction and certain hormone-related disorders such as acne and hirsutism. To avoid sexually transmitted disease, barrier protection should be used along with oral contraceptives until mutually monogamous, stable relationships are established. Healthy older women who are nonsmokers may also safely use currently available contraceptives. These agents have little impact on metabolic parameters linked to the development of cardiovascular disease. In addition to providing reliable contraception, oral contraceptives offer noncontraceptive benefits to older reproductive-age women, including control of abnormal bleeding and a reduction in the incidence of ovarian and endometrial cancers and other gynecologic pathology. Intrauterine devices and progestin implants are safe, effective, and underused in the United States. Progestin implants may have an additional role in patients for whom estrogen preparations are contraindicated. Counseling is very important before insertion because of the high rate of nuisance side effects. The contraception selection process must consider the efficacy and acceptability of the specific method to avoid the probability of unintended pregnancy and the risk of sexually transmitted diseases.
近年来,美国报告的意外怀孕率最高以及出生人数增加最多的群体是青少年和35岁以上的女性。越来越多的这类女性将需要避孕以避免意外怀孕。对于青少年,复方口服避孕药可间接保护生育能力,并对月经功能紊乱以及某些激素相关疾病(如痤疮和多毛症)产生有益作用。为避免性传播疾病,在建立相互一夫一妻制的稳定关系之前,应在使用口服避孕药的同时使用屏障保护措施。不吸烟的健康老年女性也可安全使用现有的避孕药具。这些药物对与心血管疾病发展相关的代谢参数影响很小。除了提供可靠的避孕措施外,口服避孕药还为年龄较大的育龄女性带来非避孕益处,包括控制异常出血以及降低卵巢癌、子宫内膜癌和其他妇科疾病的发病率。宫内节育器和孕激素植入剂在美国是安全、有效的,但使用不足。孕激素植入剂在禁忌使用雌激素制剂的患者中可能有额外作用。由于烦人的副作用发生率较高,在植入前进行咨询非常重要。避孕方法的选择过程必须考虑特定方法的有效性和可接受性,以避免意外怀孕的可能性和性传播疾病的风险。