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长期使用二丙酸倍氯米松控制儿童重症哮喘。

The long-term use of beclomethasone dipropionate for the control of severe asthma in children.

作者信息

Lee-Hong E, Collins-Williams C

出版信息

Ann Allergy. 1977 Apr;38(4):242-4.

PMID:851256
Abstract

Thirty-nine children with severe asthma who had been treated with aerosol inhalations of beclomethasone dipropionate for 33 to 34 months were studied. Twenty-eight were still benefitting from the drug, thrush had occurred in three, and only six of the 20 originally steroid-dependent now required steroid orally. The authors feel that this is an efficacious, safe medication but stress that systemic steroid therapy should be promptly reinstituted during acute exacerbations in steroid-dependent patients.

摘要

对39名患有严重哮喘的儿童进行了研究,这些儿童接受二丙酸倍氯米松气雾剂吸入治疗33至34个月。28名儿童仍从该药中获益,3名儿童出现了鹅口疮,最初20名依赖类固醇的儿童中只有6名现在需要口服类固醇。作者认为这是一种有效、安全的药物,但强调在依赖类固醇的患者急性加重期间应立即重新开始全身类固醇治疗。

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