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1943 - 1987年丹麦癌症患者的生存情况。女性生殖器官。

Survival of Danish cancer patients 1943-1987. Female genital organs.

作者信息

Kjaer S K, Storm H H

机构信息

Danish Cancer Society, Division for Cancer Epidemiology, Copenhagen.

出版信息

APMIS Suppl. 1993;33:107-21.

PMID:8512734
Abstract

In Denmark, about 1800 new cases of cancer of the female genital organs (i.e., uterine cervix, uterine corpus and ovary) occur every year. The similarity in incidence contrasts with the differences in survival patterns for these three cancer types, the crude five-year survival rates being 59% (cervix), 68% (corpus) and 27% (ovary). An overall increase in relative one-, two- and five-year survival rates was observed for cancers of the cervix, corpus and ovary between 1943 and 1987. For uterine cervical cancer there has been an equal improvement in one-, two- and five-year survival rates (12, 11 and 14%), whereas for uterine corpus cancer a greater improvement was seen in the five-year rates (19%) than in those one year after diagnosis (10%). These figures are contrasted by those for ovarian cancer, for which the improvement in one-year survival rate (21%) was nearly twice that for the five-year survival rate (12%). For all the three cancer types, the age at diagnosis increased significantly over the past 40 years. The improvement in survival from cancer of the uterine corpus was most pronounced for older women whereas that for ovarian cancer was greatest among women aged 59 or less. After 1970, there was a decrease in survival rates after cervical cancer among women 60 years or older at the time of diagnosis. This is in contrast to the pattern for younger women (less than 40 at diagnosis), whose survival rate has increased continuously since 1943.

摘要

在丹麦,每年约有1800例女性生殖器官癌症(即子宫颈癌、子宫体癌和卵巢癌)新发病例。这三种癌症类型的发病率相似,但生存模式存在差异,其粗略的五年生存率分别为59%(子宫颈癌)、68%(子宫体癌)和27%(卵巢癌)。1943年至1987年间,子宫颈癌、子宫体癌和卵巢癌的相对1年、2年和5年生存率总体呈上升趋势。子宫颈癌的1年、2年和5年生存率均有相同程度的提高(分别为12%、11%和14%),而子宫体癌的5年生存率提高幅度(19%)大于诊断后1年的生存率提高幅度(10%)。这些数据与卵巢癌形成对比,卵巢癌1年生存率的提高幅度(21%)几乎是5年生存率提高幅度(12%)的两倍。在过去40年里,所有这三种癌症类型的诊断年龄均显著增加。子宫体癌生存率的提高在老年女性中最为明显,而卵巢癌生存率的提高在59岁及以下女性中最为显著。1970年以后,诊断时年龄在60岁及以上的女性子宫颈癌患者的生存率有所下降。这与年轻女性(诊断时年龄小于40岁)的情况相反,自1943年以来,年轻女性的生存率持续上升。

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