Møller H, Friis S, Kjaer S K
Danish Cancer Society, Division for Cancer Epidemiology, Copenhagen.
APMIS Suppl. 1993;33:122-36.
This chapter describes the survival of men with the two commonest cancers of the genital organs--cancer of the prostate and cancer of the testis. Prostatic cancer is largely a disease of old age and occurs at a rate of about 1400 new cases per year in Denmark. Testicular cancer is a rare disease, usually affecting men in their 20s and 30s. About 250 new cases occur annually in Denmark. Both prostatic and testicular cancer have been increasing in incidence over the period of cancer registration in Denmark. Relative survival of prostatic cancer patients improved over the period of study, with an increase in one-year survival from 52% around 1945 to 80% around 1985. The corresponding change in five-year survival was from 22 to 39%. The survival of testicular cancer patients increased in response to improvements in therapy: relative one-year survival increased from 70% around 1945 to 95% around 1985. The increase was particularly strong for non-seminomas, for which one-year survival increased from 53 to 94%. Excess mortality after a diagnosis of testicular cancer was most pronounced in the first few years after diagnosis; for prostatic cancer, mortality relative to that of the general population was about two fold, even 10 years after diagnosis.
本章描述了患有两种最常见生殖器官癌症——前列腺癌和睾丸癌的男性的生存情况。前列腺癌主要是一种老年疾病,在丹麦每年约有1400例新发病例。睾丸癌是一种罕见疾病,通常影响二三十岁的男性。丹麦每年约有250例新发病例。在丹麦癌症登记期间,前列腺癌和睾丸癌的发病率都在上升。在研究期间,前列腺癌患者的相对生存率有所提高,一年生存率从1945年左右的52%上升到1985年左右的80%。五年生存率的相应变化从22%升至39%。睾丸癌患者的生存率因治疗改善而提高:相对一年生存率从1945年左右的70%升至1985年左右的95%。非精原细胞瘤的生存率提高尤为显著,其一年生存率从53%升至94%。睾丸癌诊断后的超额死亡率在诊断后的头几年最为明显;对于前列腺癌,相对于普通人群的死亡率即使在诊断后10年也约为两倍。