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运动想象可局部激活小脑。一项使用99mTc-HMPAO的单光子发射计算机断层扫描局部脑血流研究。

Motor imagery activates the cerebellum regionally. A SPECT rCBF study with 99mTc-HMPAO.

作者信息

Ryding E, Decety J, Sjöholm H, Stenberg G, Ingvar D H

机构信息

Department of Clinical Neurophysiology, University Hospital, Lund, Sweden.

出版信息

Brain Res Cogn Brain Res. 1993 Apr;1(2):94-9. doi: 10.1016/0926-6410(93)90015-w.

DOI:10.1016/0926-6410(93)90015-w
PMID:8513244
Abstract

Our earlier findings of a cerebellar activation during motor imagery (Brain Res., 535 (1990) 313-317) were made with a technique with low regional resolution. Therefore we could not elucidate the distribution of the cerebellar activation. In the present study the cerebellar regional cerebral blood flow (rCBF) changes during motor imagery (MI) was measured with a single photon emission computed tomography (SPECT) rCBF method (99mTc-HMPAO) with higher regional resolution during (1) silent counting, and (2) MI (which included silent counting) in 17 normal subjects. Comparing the SPECT results from the two tasks revealed the regional activations during MI. We confirmed that the most pronounced regional activations during MI were found in the cerebellum, especially in its infero-lateral parts on both sides.

摘要

我们早期关于运动想象时小脑激活的研究结果(《脑研究》,535卷(1990年)313 - 317页)是采用区域分辨率较低的技术得出的。因此,我们无法阐明小脑激活的分布情况。在本研究中,运用单光子发射计算机断层扫描(SPECT)脑血流量(rCBF)方法(99mTc - HMPAO),对17名正常受试者在(1)静息计数和(2)运动想象(包括静息计数)过程中小脑区域脑血流量(rCBF)的变化进行了测量,该方法具有更高的区域分辨率。比较两项任务的SPECT结果,揭示了运动想象期间的区域激活情况。我们证实,运动想象期间最显著的区域激活出现在小脑,尤其是两侧的下外侧部分。

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