豚鼠包涵体结膜炎病原体（鹦鹉热衣原体）主要外膜蛋白基因缺乏等位基因多态性。
Lack of allelic polymorphism for the major outer membrane protein gene of the agent of guinea pig inclusion conjunctivitis (Chlamydia psittaci).
作者信息
Zhao Q, Schachter J, Stephens R S
机构信息
Department of Laboratory Medicine, University of California, San Francisco 94143-0412.
出版信息
Infect Immun. 1993 Jul;61(7):3078-80. doi: 10.1128/iai.61.7.3078-3080.1993.
Abstract
The major outer membrane protein gene (omp1) was sequenced for each of six Chlamydia psittaci (guinea pig inclusion conjunctivitis [GPIC]) strains isolated from guinea pigs. Five of the isolates were obtained in the United States during the 1960s and 1970s, including the prototype strain isolated by Murray in 1962. The other isolate was obtained from a guinea pig in England. The nucleotide sequence of the omp1 gene for each strain was identical. The lack of omp1 allelic polymorphism among GPIC isolates suggests that, unlike C. trachomatis, the GPIC agent lacks antigenic variation in the major outer membrane protein.
摘要
对从豚鼠分离出的6株鹦鹉热衣原体（豚鼠包涵体结膜炎[GPIC]）菌株的主要外膜蛋白基因（omp1）进行了测序。其中5株分离株是在20世纪60年代和70年代在美国获得的，包括1962年由默里分离出的原型菌株。另一株分离株是从英国的一只豚鼠身上获得的。每个菌株的omp1基因的核苷酸序列是相同的。GPIC分离株中omp1等位基因多态性的缺乏表明，与沙眼衣原体不同，GPIC病原体在主要外膜蛋白中缺乏抗原变异。
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