血清抗体在衣原体性生殖器感染免疫中的保护作用。
Protective role of serum antibody in immunity to chlamydial genital infection.
作者信息
Rank R G, Batteiger B E
机构信息
Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock 72205.
出版信息
Infect Immun. 1989 Jan;57(1):299-301. doi: 10.1128/iai.57.1.299-301.1989.
Abstract
Female guinea pigs were injected intraperitoneally with pooled immunoglobulin derived from animals immunized to the chlamydial agent of guinea pig inclusion conjunctivitis. Genital infections in animals receiving pooled immunoglobulin from immune animals were markedly decreased with regard to the number of inclusions detected compared with control animals. These data indicated that serum-derived antibody was able to provide a degree of protection against a chlamydial genital tract infection.
摘要
给雌性豚鼠腹腔注射从免疫豚鼠包涵体结膜炎衣原体病原体的动物中提取的混合免疫球蛋白。与对照动物相比，接受来自免疫动物的混合免疫球蛋白的动物的生殖器感染，在所检测到的包涵体数量方面明显减少。这些数据表明，血清来源的抗体能够提供一定程度的保护，抵御衣原体生殖道感染。
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本文引用的文献
1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
Antibodies to Chlamydia trachomatis in cervicovaginal secretions: relation to serum antibodies and current chlamydial infection.
Sex Transm Dis. 1980 Jan-Mar;7(1):11-5. doi: 10.1097/00007435-198001000-00003.
3
Serum and tear antibodies to Chlamydia after reinfection with guinea pig inclusion conjunctivitis agent.豚鼠包涵体结膜炎病原体再次感染后血清及泪液中抗衣原体抗体
Invest Ophthalmol Vis Sci. 1981 Dec;21(6):833-41.
4
Correlation of host immune response with quantitative recovery of Chlamydia trachomatis from the human endocervix.宿主免疫反应与沙眼衣原体从人宫颈定量恢复之间的相关性。
Infect Immun. 1983 Mar;39(3):1491-4. doi: 10.1128/iai.39.3.1491-1494.1983.
5
Humoral immune response in acquired immunity to chlamydial genital infection of female guinea pigs.雌性豚鼠衣原体性生殖道感染获得性免疫中的体液免疫反应。
Infect Immun. 1983 Jan;39(1):463-5. doi: 10.1128/iai.39.1.463-465.1983.
6
Effect of antithymocyte serum on the course of chlamydial genital infection in female guinea pigs.抗胸腺细胞血清对雌性豚鼠衣原体性生殖道感染病程的影响。
Infect Immun. 1983 Aug;41(2):876-9. doi: 10.1128/iai.41.2.876-879.1983.
7
Clinical importance of the biochemical changes in the female genital tract. I. Studies on the proteins of cervical mucus.女性生殖道生化变化的临床重要性。I. 宫颈黏液蛋白质的研究。
Int J Fertil. 1969 Jan-Mar;14(1):1-7.
8
9
10
Immunity to chlamydial infections of the eye. V. Passive transfer of antitrachoma antibodies to owl monkeys.眼部衣原体感染的免疫性。V. 抗沙眼抗体向夜猴的被动转移。
Infect Immun. 1973 Apr;7(4):600-3. doi: 10.1128/iai.7.4.600-603.1973.
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