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[Blalock-Taussig分流术后肺动脉的生长及形态学评估]

[Growth of the pulmonary arteries and morphological assessment after Blalock-Taussig shunts].

作者信息

Honda J

机构信息

Department of Thoracic Surgery, Nippon Medical School, Tokyo, Japan.

出版信息

Nihon Kyobu Geka Gakkai Zasshi. 1993 Apr;41(4):569-77.

PMID:8515154
Abstract

Clinical and angiographic results were studied after 121 classic Blalock-Taussig shunts (CBT) and 74 modified Blalock-Taussig shunts (MBT) with polytetrafluoroethylene grafts. 1. The actuarial shunt patency rate in all 195 patients showed a significant difference in patency between CBT and MBT at six months after operation. (CBT = 91.6%, MBT = 98.6%, p < 0.05). The patency rate of 4-mm MBT grafts was lower than that of CBT of grafts. 2. The 109 patients who underwent postoperative angiography were evaluated for morphological features of anastomosis. The incidence of pulmonary arterial stenosis caused by anastomosis was 15.3% with CBT and 18.9% with MBT; these values were not significantly different. The primary characteristic of CBT anastomosis was a funnel-shaped stenosis at the side of shunt vessel, but this feature did not disturb pulmonary artery growth. In contrast, MBT grafts sometimes narrowed along their entire length, causing deterioration of pulmonary artery growth. 3. The 60 patients in whom pre- and post-operative pulmonary artery sizes were able to be evaluated were studied for pulmonary artery growth. The development ratio (DR) was calculated as the ratio of postoperative to preoperative pulmonary artery index (post-PAI/pre-PAI). a) DR in patients with lower preoperative PAI was greater than that in patients with higher preoperative PAI. b) DR in patients under the age of 6 months was greater than that in older patients. c) There were no significant differences in DR between CBT and MBT or between pulmonary stenosis and pulmonary atresia. d) Relative to the BT shunt, the ipsilateral pulmonary artery grew to the same degree as the contralateral artery.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

对121例采用经典Blalock-Taussig分流术(CBT)和74例采用聚四氟乙烯移植物的改良Blalock-Taussig分流术(MBT)后的临床和血管造影结果进行了研究。1. 所有195例患者的分流管实际通畅率显示,术后6个月时CBT和MBT在通畅性方面存在显著差异。(CBT = 91.6%,MBT = 98.6%,p < 0.05)。4毫米MBT移植物的通畅率低于CBT移植物。2. 对109例行术后血管造影的患者进行了吻合口形态特征评估。CBT导致的肺动脉狭窄发生率为15.3%,MBT为18.9%;这些值无显著差异。CBT吻合口的主要特征是分流血管侧的漏斗状狭窄,但该特征未干扰肺动脉生长。相比之下,MBT移植物有时会沿其全长变窄,导致肺动脉生长恶化。3. 对60例术前和术后肺动脉大小可评估的患者进行了肺动脉生长研究。发育率(DR)计算为术后与术前肺动脉指数之比(术后PAI/术前PAI)。a)术前PAI较低的患者的DR高于术前PAI较高的患者。b)6个月以下患者的DR高于年龄较大的患者。c)CBT和MBT之间或肺动脉狭窄与肺动脉闭锁之间的DR无显著差异。d)相对于BT分流术,同侧肺动脉与对侧动脉生长程度相同。(摘要截取自250字)

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