Rayne S C, Kraus F T
Department of Pathology, St. John's Mercy Medical Center, St. Louis, Missouri.
Pathol Res Pract. 1993 Feb;189(1):2-17. doi: 10.1016/S0344-0338(11)80111-1.
Vascular lesions, most often mediated by thrombi, are second only to infections as a cause of fetal injury in the later weeks of pregnancy. In our experience many pathologists who examine placentas fail to conduct a proper search for vascular lesions and some even fail to recognize those exposed by their examination. This review is intended to define the typical clinical background or circumstances that suggest the presence of significant vascular problems, to define techniques calculated to display them well, and to identify criteria for diagnosis. Further research is needed to evaluate the prevalence of maternal and fetal hypercoagulable states and thrombi as a cause of fetal injury.
血管病变，多数情况下由血栓介导，是妊娠晚期仅次于感染的胎儿损伤原因。根据我们的经验，许多检查胎盘的病理学家未能对血管病变进行恰当排查，有些甚至未能识别出检查中所暴露的病变。本综述旨在明确提示存在重大血管问题的典型临床背景或情况，确定能良好显示这些病变的技术，并确定诊断标准。需要进一步研究以评估母体和胎儿高凝状态及血栓作为胎儿损伤原因的发生率。
