Degryse H, De Schepper A, Verlinden M
Dept. of Radiology and Medical Imaging, University Hospital Antwerp, Belgium.
Scand J Gastroenterol Suppl. 1993;195:1-4. doi: 10.3109/00365529309098321.
Twenty patients with functional dyspepsia were referred for radiologic examination and, upon confirmation of a hypomotile stomach, were given either 10 mg cisapride or placebo in a double-blind manner (10 patients per group). The movement of a 250-ml barium meal was assessed by means of television fluoroscopy performed at regular time intervals. Cisapride significantly improved antral contractility and enhanced gastric emptying compared with placebo. Deep peristaltic waves occurred over the entire small bowel, and motility and small-bowel transit time of the barium meal were significantly increased in the cisapride group compared with the placebo group. The study demonstrates that when a carefully defined protocol is observed, fluoroscopy following barium ingestion offers considerable potential in the assessment of gastrointestinal motility.
20例功能性消化不良患者被转诊接受放射学检查，在确认胃动力不足后，以双盲方式给予10 mg西沙必利或安慰剂（每组10例患者）。通过定期进行的电视荧光透视法评估250 ml钡餐的移动情况。与安慰剂相比，西沙必利显著改善了胃窦收缩力并增强了胃排空。整个小肠出现了深蠕动波，与安慰剂组相比，西沙必利组钡餐的蠕动和小肠通过时间显著增加。该研究表明，当遵循精心定义的方案时，吞钡后的荧光透视法在评估胃肠动力方面具有相当大的潜力。
