Forastiero R R, Falcón C, Rodrigué S, Kordich L C, Carreras L O
Sección Hemostasia y Trombosis, Hospital de Clínicas, Facultad de Medicina, Universidad de Buenos Aires, Argentina.
Sangre (Barc). 1993 Apr;38(2):147-9.
Lupus anticoagulant activity and anti-phospholipid antibodies (aPL) were found in a six-year-old child with cerebral ischemic infarction in the absence of any underlying disease. The association of these antibodies with thrombosis has been well documented in adult patients. In view of our observation, we believe that aPL may also be involved in the pathogenesis of arterial thrombotic events in childhood, and aPL should be systematically searched in these cases.
在一名无任何基础疾病的六岁儿童中发现了狼疮抗凝活性和抗磷脂抗体(aPL),该患儿患有脑缺血性梗死。这些抗体与血栓形成的关联在成年患者中已有充分记录。鉴于我们的观察结果,我们认为aPL也可能参与儿童期动脉血栓形成事件的发病机制,在这些病例中应系统地检测aPL。