Wrathall A E, Broughton E S, Gill K P, Goldsmith G P
Central Veterinary Laboratory, Addlestone, Surrey.
Vet Rec. 1993 May 1;132(18):449-54. doi: 10.1136/vr.132.18.449.
Until and including 1987 diagnostically significant serological titres to swine brucellosis had occurred in the serum agglutination test (SAT) or the complement fixation test (CFT), ie, > or = 100 iu or > or = 20 icftu, respectively, almost every year since reliable records began, but usually only about 0.05 per cent in the SAT and 0.005 per cent in the CFT. Brucella suis was never isolated by cultural examination. In 1988 the level of CFT reactions > or = 20 icftu rose to 0.42 per cent (1.04 per cent in the last quarter of the year) but the SAT reactions remained relatively unchanged. In 1989 the levels of both CFT and SAT reactions increased further with CFT reactions again predominating. Analyses of the serological reaction patterns in individual herds suggested that infection with brucella or some other organism capable of causing serological cross-reactions had become widespread in Great Britain, although signs of disease typical of swine brucellosis had not been observed. Some herds had reactions which persisted for many months whereas others showed them for only a short time. In early 1990 Yersinia enterocolitica serogroup O:9 was isolated from some pigs purchased from one of the reactor herds and this organism is probably responsible for the increased numbers of seroreactions. It had not previously been found in pigs in Great Britain.
直到1987年（含1987年），自可靠记录开始以来，几乎每年在血清凝集试验（SAT）或补体结合试验（CFT）中都会出现具有诊断意义的猪布鲁氏菌病血清学效价，即分别≥100国际单位或≥20补体结合单位，但在SAT中通常仅约0.05%，在CFT中为0.005%。通过培养检查从未分离出猪布鲁氏菌。1988年，补体结合试验反应≥20补体结合单位的水平升至0.42%（该年最后一个季度为1.04%），但血清凝集试验反应相对保持不变。1989年，补体结合试验和血清凝集试验反应水平均进一步上升，补体结合试验反应再次占主导。对个别猪群血清学反应模式的分析表明，布鲁氏菌或其他能够引起血清学交叉反应的生物体感染在英国已广泛传播，尽管未观察到典型的猪布鲁氏菌病症状。一些猪群的反应持续数月，而另一些猪群的反应仅持续很短时间。1990年初，从一个反应猪群购买的一些猪中分离出了小肠结肠炎耶尔森菌O:9血清群，这种生物体可能是血清反应增多的原因。此前在英国的猪中未发现过这种细菌。
