Harris A P, Sendak M J, Chung D C, Richardson C A
Department of Anesthesiology/Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Am J Perinatol. 1993 May;10(3):250-4. doi: 10.1055/s-2007-994731.
The noninvasive measurement of fetal arterial oxygen saturation using pulse oximetry could be of potential use in assessing fetal well-being in utero during labor. In this study, the accuracy and technical feasibility of reflectance pulse oximetry in utero was evaluated in acutely instrumented fetal sheep using a specially designed sensor. Following recalibration of the analysis algorithms, fetal arterial saturation could be measured by pulse oximetry in utero. Arterial oxygenation measurements obtained using pulse oximetry correlated well with simultaneous in vitro measurements over the range of 6 to 81%. We conclude that in utero pulse oximetry is technically feasible, appears useful and accurate, and merits further evaluation.
使用脉搏血氧饱和度仪对胎儿动脉血氧饱和度进行无创测量，可能在评估分娩期间子宫内胎儿的健康状况方面具有潜在用途。在本研究中，使用专门设计的传感器，对急性植入仪器的胎羊评估了子宫内反射式脉搏血氧饱和度仪的准确性和技术可行性。在重新校准分析算法后，可通过子宫内脉搏血氧饱和度仪测量胎儿动脉饱和度。使用脉搏血氧饱和度仪获得的动脉氧合测量值与6%至81%范围内的同步体外测量值相关性良好。我们得出结论，子宫内脉搏血氧饱和度仪在技术上是可行的，似乎有用且准确，值得进一步评估。
