Rubin B G, Santoro S A, Sicard G A
Department of Surgery, Washington University School of Medicine, St. Louis, MO.
Ann Vasc Surg. 1993 Mar;7(2):200-7. doi: 10.1007/BF02001017.
Most physicians are aware of the important role that platelets play in thrombus formation. The mechanisms that regulate platelet function are now understood at the molecular level. The same biologic processes that control platelet participation in the hemostatic process also allow platelets to interact with the vessel wall. This review will describe the interaction of platelets with the vessel wall and prosthetic grafts and the physiologic basis and clinical contribution of platelet inhibition to long-term graft patency.
大多数医生都知道血小板在血栓形成中所起的重要作用。目前，调节血小板功能的机制已在分子水平上得到了解。控制血小板参与止血过程的相同生物学过程也使血小板能够与血管壁相互作用。本综述将描述血小板与血管壁及人工血管移植物的相互作用，以及血小板抑制对移植物长期通畅的生理基础和临床意义。
